CURRICULUM
VITAE
Michael V. Cohen, M.D.
Office Address (Clinical): University of South
Alabama Medical Center
Division of Cardiology
2451 Fillingim Street
Mobile, Alabama 36617
Office
Phone: (251) 471-7915
Office Address (Research): Department of Physiology
MSB 3050
University of South Alabama
College of Medicine
Mobile,
AL 36688
Office
Phone: (251) 460-6812
Education:
Harvard College, A.B. (summa cum
laude) 1964
Harvard Medical School, M.D. (cum
laude) 1968
Postgraduate Training:
Medical
Intern, II and IV (Harvard) Medical Service
Boston City Hospital, Boston 1968-1969
Assistant Resident in Internal Medicine, II and IV
(Harvard)
Medical Service Boston City Hospital, Boston
1969-1970
Fellow in Cardiology
Peter Bent Brigham Hospital, Boston 1970-1972
Research Associate in Internal Medicine
Peter Bent Brigham Hospital, Boston 1972-1973
Professional Employment and Hospital
Appointments:
Instructor in Medicine
Harvard University School of
Medicine 1973
Assistant Professor of Medicine
Albert Einstein College of Medicine,
New York 1974-1979
Assistant Attending Physician
Montefiore Hospital and Medical
Center 1974-1977
Adjunct Attending Physician
Montefiore Hospital and Medical
Center 1974-1984
Associate Professor of Medicine
Albert Einstein College of Medicine,
New York 1979-1984
Professor of Medicine
Albert Einstein College of Medicine, New York
1984-1991
Associate Attending Physician
Montefiore Medical Center 1984-1991
Professor of Medicine and Physiology
Professor
of Physiology and Medicine
Distinguished
University Professor
University of South Alabama, Mobile,
AL 1991-present
Board Certification:
American Board of Internal Medicine
June, 1972
Cardiovascular Subspecialty Board
March,1974
Professional Society Memberships:
American Federation for Medical Research
American College of Cardiology
American Heart Association
American Society for Clinical Investigation
Awards and Honors:
Special Research Fellowship
National Institutes of Health 1973
Research Career Development Award
National Institutes of Health 1977-1981
NRSA Senior Fellowship
National Institutes of Health 1987
Distinguished University Professor
University of South Alabama, Mobile, AL 1991- present
Other Professional Activities:
Coordinating Committee, Montefiore Medical Center
New York City Echo Club, Co-Director
Private Practice Committee, Montefiore Medical Center
Animal Care Committee, Montefiore Medical Center
Executive Council, University of South Alabama
College of Medicine
Research Committee, University of South Alabama
College of Medicine
Institutional Animal Care and Use Committee,
University of South Alabama College of Medicine
Utilization Review Committee, University of South
Alabama Medical Center
Medication Use Committee, University of South Alabama
Medical Center
Promotion and Tenure Committee, Department of
Medicine, University of South Alabama College of Medicine
Faculty Senate, University of South Alabama College
of Medicine
Faculty Committee on Appointment, Promotion, and
Evaluation, University of South Alabama College of Medicine
Graduate School Directorship/Governance Committee,
University of South Alabama College of Medicine
Study Section:
Respiratory and Applied Physiology 1983-1986
National Institutes of Health
Clinical & Integrative CV
Physiology/Pathophysiology
American
Heart Association 1998-2001
Cardiovascular
Pathophysiology I
American Heart Association 2002-2004
Editorial Board:
Basic Research in Cardiology 1999-present
Heart Disease: A Journal of Cardiovascular Medicine
1999-2004
Bibliography
– Published
1.
Forman,
S.E., Durbetaki, A.J., Cohen, M.V., and Olofson, R.A.: Conformational Equilibria in Cyclic Sulfites
and Sulfates. The Configurations and
Conformations of the Two Isomeric Thiodans.
Journal of Organic Chemistry 30: 169-175, 1965.
2.
Cohen,
M.V., Cohn, P.F., Herman, M.V., and Gorlin, R.: Diagnosis and Prognosis of Main Left Coronary Artery
Obstruction. Circulation 45:
I-57-I-65, 1972.
3.
Cohen,
M.V.: Ventricular Fibrillation
Precipitated by Carotid Sinus Pressure:
Case Report and Review of the Literature. American Heart Journal 84: 681-686, 1972.
4.
Cohen,
M.V., and Gorlin, R.: Modified Orifice
Equation for the Calculation of Mitral Valve Area. American Heart Journal 84: 839-840, 1972.
5.
Cohen,
M.V., and Eldh, P.: Experimental
Myocardial Infarction in the Closed-Chest Dog:
Controlled Production of Large or Small Areas of Necrosis. American Heart Journal 86: 798-804,
1973.
6.
Cohen,
M.V., and Kirk, E.S.: Differential
Response of Large and Small Coronary Arteries to Nitroglycerin and Angiotensin:
Autoregulation and Tachyphylaxis.
Circulation Research 33: 445-453, 1973.
7.
Cohen,
M.V., Downey, J.M., Sonnenblick, E.H., and Kirk, E.S.: The Effects of Nitroglycerin on Coronary
Collaterals and Myocardial Contractility.
Journal of Clinical Investigation 52: 2836-2847, 1973.
8.
Cohen,
M.V., Chahine, R.A., Klein, M.D., and Gorlin, R.: The Effect of Acetylstrophanthidin on Systolic Time Intervals in
the Non-Failing Human Heart. Journal of
Pharmacology and Experimental Therapeutics 191: 487-495, 1974.
9.
Teichholz,
L.E., Cohen, M.V., Sonnenblick, E.H., and Gorlin, R.: Study of Left Ventricular Geometry and Function by B-Scan
Ultrasonography in Patients With and Without Asynergy. New England Journal of Medicine 291:
1220-1226, 1974.
10.
Bergeron,
G., Cohen, M.V., Teichholz, L.E., and Gorlin, R.: Echocardiographic Analysis of Mitral Valve Motion after Acute
Myocardial Infarction. Circulation 51:
82-87, 1975.
11.
Cohen,
M.V., and Gorlin, R.: Main Left
Coronary Artery Disease: Clinical Experience
from 1964-1974. Circulation 52:
275-285, 1975.
12.
Cohen,
M.V., Cooperman, L.B., and Rosenblum, R.:
Regional Myocardial Function in Idiopathic Hypertrophic Subaortic
Stenosis: An Echocardiographic Study. Circulation 52: 842-847, 1975.
13.
Cohen,
M.V.: Double Mitral Leaflet
Prolapse:
Echocardiographic-Phonocardiographic Correlation. American Heart Journal 91: 168-177,
1976.
14.
Cohen,
M.V., Sonnenblick, E.H., and Kirk, E.S.:
Comparative Effects of Nitroglycerin and Isosorbide Dinitrate on
Coronary Collateral Vessels and Ischemic Myocardium. American Journal of Cardiology 37: 244-249, 1976.
15.
Cohen,
M.V., Teichholz, L.E., and Gorlin, R.:
B-Scan Ultrasonography: Study of
Left Ventricular Outflow Tract and Pathophysiologic Mechanism of Obstruction in
Idiopathic Hypertrophic Subaortic Stenosis.
British Heart Journal 38: 595-604, 1976.
16.
Cohen,
M.V., Sonnenblick, E.H., and Kirk, E.S.:
Coronary Steal: Role in the
Detrimental Effect of Isoproterenol Following Acute Coronary Occlusion. American Journal of Cardiology 38:
880-888, 1976.
17.
Greenberg,
M.A., and Cohen, M.V.: Bedside
Maneuvers in the Diagnosis of Cardiac Murmurs.
Hospital Physician 13(11): 24-26, 1977.
18.
Goldberg,
S., Grossman, W., Markis, J.E., Cohen, M.V., Baltaxe, H.A., and Levin,
D.C.: Total Occlusion of the Left Main
Coronary Artery: A Clinical, Hemodynamic
and Angiographic Profile. American Journal of Medicine 64: 3-8, 1978.
19.
Gross,
H., Vaid, A.K., and Cohen, M.V.:
Prognosis in Patients Rejected for Coronary Revascularization
Surgery. American Journal of Medicine 64:
9-20, 1978.
20.
Cohen,
M.V.: The Functional Value of Coronary
Collaterals in Myocardial Ischemia and Therapeutic Approach to Enhance
Collateral Flow. American Heart Journal
95: 396-404, 1978.
21.
Cohen,
M.V.: Quantitation of Collateral and
Ischemic Flows with Microspheres and Diffusible Indicator. American Journal of Physiology 234:
H487-H495, 1978.
22.
Cohen,
M.V.: Real-Time Sector Scan Study of
the Mitral Valve Prolapse Syndrome. British Heart Journal 40: 964-971,
1978.
23.
Cohen,
M.V., Yipintsoi, T., Malhotra, A., Penpargkul, S., and Scheuer, J.: Effect of Exercise on Coronary Collateral
Development in Dogs with Normal Coronary Arteries. Journal of Applied Physiology 45: 797-805, 1978.
24.
Cohen,
M.V., Shah, P.K., and Spindola-Franco, H.:
Angiographic- Echocardiographic Correlation in Mitral Valve
Prolapse. American Heart Journal 97:
43-52, 1979.
25.
Cohen,
M.V., and Greenberg, M.A.: Constrictive
Pericarditis: Early and Late
Complication of Cardiac Surgery.
American Journal of Cardiology 43: 657-661, 1979.
26.
Cohen,
M.V.: Left Atrial Myxoma: Echocardiographic Identification. Journal of
the Medical Society of New Jersey 76: 213-215, 1979.
27.
Greenberg,
M.A., Herman, L.S., and Cohen, M.V.:
Mitral Valve Closure in Atrial Flutter.
Circulation 59: 902-909, 1979.
28.
Rosenthal,
R., Kleid, J., and Cohen, M.V.:
Abnormal Mitral Valve Motion Associated with Ventricular Septal Defect
Following Acute Myocardial Infarction.
American Heart Journal 98: 638-641, 1979.
29.
Spindola-Franco,
H., Shah, P.K., and Cohen, M.V.: Mitral
Valve Prolapse: An Angiographic and
Echocardiographic Study. In
Proceedings of the VIII World Congress of Cardiology, September, 1978, Excerpta
Medica, Amsterdam, pp. 1127-1130.
30.
Greenberg,
M.A., and Cohen, M.V.: Bedside
Maneuvers in Assessing Cardiac Murmurs.
Health Practitioner and Physician Assistant: 55-59, 1979 (July).
31.
Cohen,
M.V., Diaz, P., and Scheuer, J.:
Echocardiographic Assessment of Left Ventricular Function in Patients
with Chronic Uremia. Clinical
Nephrology 12: 156-162, 1979.
32.
Cohen,
M.V., and Yipintsoi, T.: Myocardial
Performance and Collateral Flow Following Transient Coronary Occlusion in
Exercising Dogs. American Journal of
Physiology 237: H520-H527, 1979.
33.
Cohen,
M.V.: Idiopathic Hypertrophic Subaortic
Stenosis: Echocardiographic
Characteristics. Journal of the Medical
Society of New Jersey 77: 447-449, 1980.
34.
Cohen,
M.V.: Combined Coronary Artery Disease
and Aortic Stenosis (Questions and Answers).
Journal of American Medical Association 245: 510, 1981.
35.
Cohen,
M.V., and Yipintsoi, T.: Restoration of
Cardiac Function and Myocardial Flow by Collateral Development in Dogs. American Journal of Physiology 240: H811-H819, 1981.
36.
Cohen,
M.V., Schulman, I.C., Spenillo, A., and Surks, M.I.: The Effects of Thyroid Hormone on Left Ventricular Function in Patients
Being Treated for Thyrotoxicosis.
American Journal of Cardiology 48: 33-38, 1981.
37.
Cohen,
M.V., and Yipintsoi, T.: Coronary
Collaterals: Role in Restoration of
Blood Flow and Preservation of Cardiac Function During Exercise. Basic Research in Cardiology 76:
474-479, 1981.
38.
Stern,
M.J., Cohen, M.V., Fish, B., and Rosenthal, R.: Clinical Presentation and Non-Invasive Diagnosis of Right Heart
Masses. British Heart Journal 46:
552-558, 1981.
39.
Cohen,
M.V., Yipintsoi, T., and Scheuer, J.:
Coronary Collateral Stimulation by Exercise in Dogs with Stenotic
Coronary Arteries. Journal of Applied
Physiology 52: 664-671, 1982.
40.
Cohen,
M.V.: Aortic Sclerosis and
Cerebrovascular Accidents (Questions and Answers). Journal of American Medical Association 247: 2828-2829,
1982.
41.
Grose,
R., Greenberg, M., Steingart, R., and Cohen, M.V.: Left Ventricular Volume and Function During Relief of Cardiac
Tamponade in Man. Circulation 66:
149-155, 1982.
42.
Cohen,
M.V.: Coronary Steal in Awake
Dogs: A Real Phenomenon. Cardiovascular Research 16: 339-349,
1982.
43.
Shapiro,
M.R., Cohen, M.V., Grose, R., and Spindola-Franco, H.: Diagnosis of Left Atrial
Myxoma by Coronary Angiography Nine Years following Open Mitral Commissurotomy. American Heart Journal 105: 325-327,
1983.
44.
Cohen,
M.V.: Effects of Thyroid Hormone on the
Heart in Thyrotoxicosis. Primary Cardiology 9(4): 95-106, 1983.
45.
Cohen,
M.V.: Coronary and Collateral Blood
Flows During Exercise and Myocardial Vascular Adaptations to Training. Exercise and Sport Sciences Reviews 11:
55-98, 1983.
46.
Shapiro,
M.R., and Cohen, M.V.: Review: The Echocardiogram in Cardiac
Tamponade. Journal of Cardiovascular
Ultrasonography 2: 87-95, 1983.
47.
Cohen,
M.V.: The Effects of Intracoronary
Renografin Injection on Coronary Flow and Distribution in Dogs Following
Coronary Occlusion. Basic Research in
Cardiology 78: 364-372, 1983.
48.
Shapiro,
M.R., Cohen, M.V., and Jacquette, G.:
Pulmonic Valvular Gonococcal Endocarditis: A Forgotten Disease.
British Heart Journal 50: 290-292, 1983.
49.
Rao,
P.S., Cohen, M.V., and Mueller, H.S.:
Production of Free Radicals and Lipid Peroxides in Early Experimental
Myocardial Ischemia. Journal of Molecular
and Cellular Cardiology 15: 713-716, 1983.
50.
Shapiro,
M.R., Cohen, M.V., Grose, R., and Greenberg, M.A.: Clinical and Hemodynamic Correlation in Patients with Paricardial
Effusion and Swinging Heart by Echocardiography. Journal of Clinical Ultrasound 11: 477-483, 1983.
51.
Grose,
R., Strain, J., and Cohen, M.V.:
Pulmonary Artery V Waves in Mitral Regurgitation: Clinical and Experimental Observations. Circulation 69: 214-222, 1984.
52.
Grose,
R., Greenberg, M.A., Yipintsoi, T., and Cohen, M.V.: Cardiac Tamponade in Dogs with Normal Coronary Arteries. I. Effect of Changing Intravascular Volume
on Hemodynamics and Myocardial Blood Flow.
Basic Research in Cardiology 79: 531-541, 1984.
53.
Cohen,
M.V., Greenberg, M.A., Grose, R., and Yipintsoi, T.: Cardiac Tamponade in Dogs with Normal Coronary Arteries. II.
Myocardial Flow and Metabolism with Moderate and Severe Hemodynamic
Impairment. Basic Research in
Cardiology 79: 542-550, 1984.
54.
Cohen,
M.V.: Myocardial Flow in Tamponade in
Dogs with Coronary Occlusions: Effect
of Isoproterenol. American Heart
Journal 109: 1032-1038, 1985.
55.
Cohen,
M.V., and Steingart, R.M.: Exercise
Thallium-201 Scintigraphy in Dogs:
Effects of Long-Term Coronary Occlusion and Collateral Development on Early
and Late Scintigraphic Images.
Circulation 72: 881-891, 1985.
56.
Cohen,
M.V.: Cardiology Review. Resident & Staff Physician 31(10):
137-140, 1985.
57.
Rosoff,
M.H., and Cohen, M.V.: Significance of
E Point-Septal Separation by M-Mode Echocardiography in Aortic
Regurgitation. American Journal of
Cardiology 56: 809-811, 1985.
58.
Cohen,
M.V.: Cardiology Quiz. Resident & Staff Physician 31
(11): 31 PC, 1985.
59.
Cohen,
M.V.: Cardiology Quiz. Resident & Staff Physician 31
(12): 12, 1985.
60.
Cohen,
M.V.: Isoproterenol in Cardiac
Tamponade (Letter to the Editor). American Heart Journal 110: 1318,
1985.
61.
Steingart,
R.M., and Cohen, M.V.: Thallium-201
Scintigraphic Quantitation of Regional Flow Disparity and Subsequent Redistribution
in Dogs. Journal of Nuclear Medicine 27:
75-83, 1986.
62.
Cohen,
M.V.: Cardiology Quiz. Resident & Staff Physician 32(1):
138, 1986.
63.
Cohen,
M.V.: Picture Quiz: Cardiology.
Medical Times 114(2): 101, 1986.
64.
Rosoff,
M.H., and Cohen, M.V.: Profound
Bradycardia after Amyl Nitrite in Patients with a Tendency to Vasovagal
Episodes. British Heart Journal 55: 97-100, 1986.
65.
Cohen,
M.V.: Cardiology Quiz. Resident & Staff Physician 32(2):
16PC, 21PC, 127, 1986.
66.
Cohen,
M.V.: Cardiology Quiz. Resident & Staff Physician 32(3):
44, 1986.
67.
Cohen,
M.V.: Coronary Vascular Reserve in the
Greyhound with Left Ventricular Hypertrophy.
Cardiovascular Research 20: 182-194, 1986.
68.
Cohen,
M.V.: Picture Quiz: Cardiology.
Medical Times 114(6): 85, 1986.
69.
Cohen,
M.V.: Picture Quiz: Cardiology.
Medical Times 114(8): 27, 1986.
70.
Cohen,
M.V.: Picture Quiz: Cardiology.
Medical Times 114(9): 18, 1986.
71.
Cohen,
M.V.: Cardiology Quiz. Resident & Staff Physician 32(9):
20-22, 1986.
72.
Cohen,
M.V.: Picture Quiz: Cardiology.
Medical Times 114(11): 22, 1986.
73.
Cohen,
M.V., and Steingart, R.M.: Lack of
Effect of Prior Training on Subsequent
74.
Ischemic
and Infarcting Myocardium and Collateral Development in Dogs with Normal
Hearts. Cardiovascular Research 21:
269-278, 1987.
75.
Cohen,
M.V.: Picture Quiz: Cardiology.
Medical Times 115(1): 23, 1987.
76.
Greenberg,
M.A., Grose, R.M., Neuburger, N., Silverman, R., Strain, J.E., and Cohen,
M.V.: Impaired Coronary Vasodilator
Responsiveness as a Cause of Lactate Production During Pacing-Induced Ischemia
in Patients with Angina and Normal Coronary Arteries. Journal of the American College of Cardiology 9: 743-751,
1987.
77.
Cohen,
M.V.: Picture Quiz: Cardiology.
Medical Times 115(5): 26, 1987.
78.
Cohen,
M.V.: Picture Quiz: Cardiology.
Medical Times 115(11): 112, 1987.
79.
Cohen,
M.V.: Thyrogenic Heart Disease: An Overview (Part 1). Cardiology Illustrated 3(3): 17-25,
1988.
80.
Cohen,
M.V., Matsuki, T., and Downey, J.M.:
Pressure-Flow Characteristics and Nutritional Capacity of Coronary Veins
and Their Collateral Channels in Dogs.
American Journal of Physiology 255: H834-H846, 1988.
81.
Cohen,
M.V., and Spindola-Franco, H.:
Correlation Between Left Ventriculography, Auscultation, and M-Mode and
Two-Dimensional Echocardiography in Mitral Valve Prolapse. Herz 13: 293-308, 1988.
82.
Cohen,
M.V.: Thyrogenic Heart Disease: An Overview (Part 2). Cardiology Illustrated 3(4): 3-9,
1988.
83.
Nejima,
J., Knight, D.R., Fallon, J.T., Uemura, N., Manders, W.T., Canfield, D.R.,
Cohen, M.V., and Vatner, S.F.: Superoxide
Dismutase Reduces Reperfusion Arrhythmias But Fails to Salvage Regional
Function or Myocardium at Risk in Conscious Dogs. Circulation 79: 143-153, 1989.
84.
Cohen,
M.V.: Picture Quiz: Cardiology.
Medical Times 117(2): 110, 1989.
85.
Cohen,
M.V.: Picture Quiz: Cardiology.
Medical Times 117(3): 44, 1989.
86.
Cohen,
M.V.: Picture Quiz: Cardiology.
Medical Times 117(4): 42, 1989.
87.
Matsuki,
T., Cohen, M.V., Holt, G., Ayling, J., Hearse, D.J., and Downey, J.M.: Chronic Whole Body Sympathectomy Fails to
Protect Ischemic Rabbit Hearts.
American Journal of Physiology 256: H1322-H1327, 1989.
88.
Cohen,
M.V.: Free Radicals in Ischemic and
Reperfusion Myocardial Injury: Are We
Ready for Clinical Trials? Annals of
Internal Medicine 111: 918-931, 1989.
89.
Uemura,
N., Knight, D.R., You-Tang, S., Nejima, J., Cohen, M.V., Thomas, J.X., Jr., and
Vatner, S.F.: Increased Myocardial
Infarct Size Because of Reduced Coronary Collateral Blood Flow in Beagles. American Journal of Physiology 257:
H1798-H1803, 1989.
90.
Cohen,
M.V.: Training in Dogs with Normal
Coronary Arteries: Lack of Effect on
Collateral Development. Cardiovascular
Research 24: 121-128, 1990.
91.
Matsuki,
T., Shirato, C., Cohen, M.V., and Downey, J.M.: Oxypurinol Limits Myocardial Infarct Size in Closed Chest Dogs
without Pretreatment. Canadian Journal
of Cardiology 6: 123-129, 1990.
92.
Matsuki,
T., Cohen, M.V., and Downey, J.M.: Free
Radical Scavengers Preserve Wall Motion in the Xanthine Oxidase Deficient
Rabbit Heart. Coronary Artery Disease 1:
383-389, 1990.
93.
Cohen,
M.V., and Downey, J.M.: Myocardial
Stunning in Dogs: Preconditioning
Effect and Influence of Coronary Collateral Flow. American Heart Journal 120: 282-291, 1990.
94.
Fusman,
B., Schwinger, M.E., Charney, R., Ausubel, K., and Cohen, M.V.: Isolated Collapse of Left-Sided Heart
Chambers in Cardiac Tamponade:
Demonstration by Two-Dimensional Echocardiography. American Heart Journal 121: 613-616,
1991.
95.
Cohen,
M.V., Byrne, M.-J., Levine, B., Gutowski, T., and Adelson, R.: Low Rate of Treatment of
Hypercholesterolemia by Cardiologists in Patients with Suspected and Proven
Coronary Artery Disease. Circulation 83:
1294-1304, 1991.
96.
Rosen,
S., Lahorra, M., Cohen, M.V., and Buttrick, P.: Ventricular Fibrillation Threshold Is Influenced by Left
Ventricular Stretch and Mass in the Absence of Ischaemia. Cardiovascular Research 25: 458-462,
1991.
97.
Cohen,
M.V., Liu, G.S., and Downey, J.M.:
Preconditioning Causes Improved Wall Motion as Well as Smaller Infarcts
after Transient Coronary Occlusion in Rabbits.
Circulation 84: 341-349, 1991.
98.
Cohen,
M.V.: From Calisthenics to Killing
Fields: How One Cardiologist Coped in
Kuwait. The Newspaper of Cardiology 2
(9): 24, 1991.
99.
Cohen,
M.V.: Physician Apathy About Treating
Hypercholesterolemia. Cardiology Board
Review 8 (10): 36-43, 1991.
100.
Cohen,
M.V.: Hypertrophic Cardiomyopathy: Morphologic and Physiologic
Considerations. Primary Cardiology 18
(3): 25-32, 1992.
101.
Cohen,
M.V.: Hypertrophic Cardiomyopathy: Prognosis and Treatment. Primary Cardiology 18(4): 19-40, 1992.
102.
Bunch,
F.T., Thornton, J., Cohen, M.V., and Downey, J.M.: Adenosine Is An Endogenous Protectant Against Stunning During
Repetitive Ischemic Episodes in the Heart.
American Heart Journal 124: 1440-1446,1992.
103.
Dansky,
H.M., Schwinger, M.E., and Cohen, M.V.:
Using Contrast Material-enhanced Echocardiography to Identify Abnormal
Pulmonary Arteriovenous Connections in Patients with Hypoxemia. Chest 102: 1690-1692, 1992.
104.
Cohen,
M.V.: Lack of Effect of Propranolol on
Canine Coronary Collateral Development during Progressive Coronary Stenosis and
Occlusion. Cardiovascular Research 27: 249-254, 1993.
105.
Alpert,
M.A., Terry, B.E., Lambert, C.R., Kelly, D.L., Panayiotou, H., Mukerji, V.,
Massey, C.V. and Cohen, M.V.: Factors
Influencing Left Ventricular Systolic Function in Morbidly Obese Patients: Effect of Weight Loss Induced
Gastroplasty. American Journal of
Cardiology 71: 733-737, 1993.
106.
Yang,
X.-M., Arnoult, S., Tsuchida, A., Cope, D., Thornton, J.D., Daly, J., Cohen,
M.V. and Downey, J.M.: The Protection
of Ischaemic Preconditioning Can Be Reinstated in the Rabbit Heart after the
Initial Protection Has Waned. Cardiovascular
Research 27: 556-558, 1993.
107.
Marantz,
P.R., Kuwabara, Y., Derby, C.A., Tobin, J.N., and Cohen, M.V.: Plasma Atrial Natriuretic Peptide Factor Is
Elevated In Elderly Patients With Occult Valvular Insufficiency. Cardiology in the Elderly 1: 195-201,
1993.
108.
Cohen,
M.V.: Exercise on Coronary Collaterals
(Letter to the Editor). American Heart
Journal 125: 1807, 1993.
109.
Cohen,
M.V., and Downey, J.M.: Ischaemic
Preconditioning: Can the Protection Be
Bottled? Lancet 342: 6, 1993.
110.
Cohen,
M.V., Chukwuogo, N., and Yarlagadda, A.:
Heparin Does Not Stimulate Coronary- Collateral Growth in a Canine Model
of Progressive Coronary-Artery Narrowing and Occlusion. American Journal of the Medical Sciences 306:
75-81, 1993.
111.
Liu,
Y., Thornton, J.D., Cohen, M.V., Downey, J.M., and Schaffer, S.W.: Streptozotocin-Induced Non-Insulin-Dependent
Diabetes Protects the Heart from Infarction.
Circulation 88: 1273-1278, 1993.
112.
Thornton,
J.D., Daly, J.F., Cohen, M.V., Yang, X.-M., and Downey J.M.: Catecholamines Can Induce Adenosine
Receptor-Mediated Protection of the Myocardium But Do Not Participate in
Ischemic Preconditioning in the Rabbit.
Circulation Research 73: 649-655, 1993.
113.
Cohen,
M.V.: Myocardial Ischemia Is Not a
Prerequisite for the Stimulation of Coronary Collateral Development. American Heart Journal 126: 847-855,
1993.
114.
Cohen,
M.V., Yang, X.-M., Liu, Y., Snell, K.S., and Downey, J.M.: A New Animal Model of Controlled Coronary
Artery Occlusion in Conscious Rabbits.
Cardiovascular Research 28: 61-65, 1994.
115.
Tsuchida,
A., Yang, X-M., Burckhartt, B., Mullane, K.M., Cohen, M.V., and Downey
J.M.: Acadesine Extends the Window of
Protection Afforded by Ischaemic Preconditioning. Cardiovascular Research 28: 379-383, 1994.
116.
Cohen,
M.V., Yang, X.-M., and Downey, J.M.:
Conscious Rabbits Become Tolerant to Multiple Episodes of Ischemic
Preconditioning. Circulation Research 74:
998-1004, 1994.
117.
Alpert,
M.A., Lambert, C.R., Terry, B.E., Kelly D.L., Panayiotou, H., Mukerji, V.,
Massey, C.V., and Cohen, M.V.: Effect
of Weight Loss on Left Ventricular Mass in Non-Hypertensive Morbidly Obese
Patients. American Journal of
Cardiology 73: 918-921, 1994.
118.
Cohen,
M.V., Vernon, J., Yaghdjian, V., and Hatcher, V.B.: Longitudinal Changes in Myocardial Basic Fibroblast Growth Factor
(FGF-2) Activity Following Coronary Artery Ligation in the Dog. Journal of Molecular and Cellular Cardiology
26: 683-690, 1994.
119.
Marantz,
P.R., Tobin, J.N., Derby, C.A., and Cohen, M.V.: Age-Associated Changes in Diastolic Filling: Doppler E/A Ratio Is Not Associated with
Congestive Heart Failure in the Elderly.
Southern Medical Journal 87: 728-735, 1994.
120.
Tsuchida,
A., Liu, Y., Liu, G.S., Cohen, M.V., and Downey, J.M.: α1-Adrenergic Agonists
Precondition Ischemic Myocardium Independent of Adenosine by Direct Activation
of Protein Kinase C. Circulation
Research 75: 576-585, 1994.
121.
Walsh,
R.S., Tsuchida, A., Daly, J.J.F., Thornton, J.D., Cohen, M.V., and Downey,
J.M.: Ketamine-Xylazine Anaesthesia
Permits a KATP Channel Antagonist to Attenuate Preconditioning in
Rabbit Myocardium. Cardiovascular
Research 28: 1337-1341, 1994.
122.
Charney,
R., Schwinger, M.E., Chun, J., Cohen, M.V., Nanna, M., Menegus, M.A., Wexler,
J., Franco, H.S., and Greenberg, M.A.:
Dobutamine Echocardiography and Resting-Redistribution Thallium-201
Scintigraphy Predicts Recovery of Hibernating Myocardium After Coronary
Revascularization. American Heart
Journal 128: 864-869, 1994.
123.
Ytrehus,
K., Liu, Y., Tsuchida, A., Miura, T., Liu, G.S., Yang, X.-M., Herbert, D.,
Cohen, M.V., and Downey J.M.: Rat and
Rabbit Heart Infarction: Effects of
Anesthesia, Perfusate, Risk Zone, and Method of Infarct Sizing. American Journal of Physiology 267:
H2383-H2390, 1994.
124.
Liu,
Y., Cohen, M.V., and Downey, J.M.:
Chelerythrine, a Highly Selective Protein Kinase C Inhibitor, Blocks the
Antiinfarct Effect of Ischemic Preconditioning in Rabbit Hearts. Cardiovascular Drugs and Therapy 8:
881-882, 1994.
125.
Gu,
J., Agrawal, N., Wang, P.-P., Cohen, M.V., and Downey, J.M.: A Primary-Secondary Antibody Complex Method
of Immunocytochemistry Using Rabbit Polyclonal Antibodies to Detect Antigens in
Rabbit Tissue. Cell Vision 2:
52-59, 1995.
126.
Walsh,
R.S., Borges, M., Thornton, J.D., Cohen, M.V., and Downey, J.M.: Hypoxia Preconditions Rabbit Myocardium by
an Adenosine Receptor-Mediated Mechanism.
Canadian Journal of Cardiology 11: 141-146, 1995.
127.
Liu,
Y., Tsuchida, A., Cohen, M.V., and Downey, J.M.: Pretreatment with Angiotensin II Activates Protein Kinase C and
Limits Myocardial Infarction in Isolated Rabbit Hearts. Journal of Molecular and Cellular Cardiology
27: 883-892, 1995.
128.
Cohen,
M.V., and Downey, J.M.: Preconditioning
During Ischemia: Basic Mechanisms and
Potential Clinical Applications.
Cardiology in Review 3: 137-149, 1995.
129.
Burckhartt,
B., Yang, X.-M., Tsuchida, A., Mullane, K.M., Downey, J.M., and Cohen,
M.V.: Acadesine Extends the Window of
Protection Afforded by Ischaemic Preconditioning in Conscious Rabbits. Cardiovascular Research 29: 653-657,
1995.
130.
Cohen,
M.V.: Arterial and Venous Collaterals
Salvage Ischemic Myocardium. Journal of
Myocardial Ischemia 7: 152-161, 1995.
131.
Goto,
M., Liu, Y., Yang, X.-M., Ardell, J.L., Cohen, M.V., and Downey, J.M.: Role of Bradykinin in Protection of Ischemic
Preconditioning in Rabbit Hearts.
Circulation Research 77: 611-621, 1995.
132.
Alpert,
M.A., Lambert, C.R., Terry, B.E., Cohen, M.V., Mukerji, V., Massey, C.V.,
Hashimi, M.W., and Panayiotou, H.:
Interrelationship of Left Ventricular Mass, Systolic Function and
Diastolic Filling in Normotensive Morbidly Obese Patients. International Journal of Obesity 19:
550-557, 1995.
133.
Cohen,
M.V., Walsh, R.S., Goto, M., and Downey, J.M.:
Hypoxia Preconditions Rabbit Myocardium via Adenosine and Catecholamine
Release. Journal of Molecular and
Cellular Cardiology 27: 1527-1534, 1995.
134.
Goto,
M., Tsuchida, A., Liu, Y., Cohen, M.V., and Downey, J.M.: Transient Inhibition of Glucose Uptake
Mimics Ischemic Preconditioning by Salvaging Ischemic Myocardium in the Rabbit
Heart. Journal of Molecular and Cellular
Cardiology 27: 1883-1894, 1995.
135.
Cohen,
M.V., Snell, K.S., Tsuchida, A., Van Wylen, D.G.L., and Downey, J.M.: Effects of Anesthesia and K+ ATP
Channel Blockade on Interstitial Adenosine Accumulation in Ischemic Rabbit
Myocardium. Basic Research in
Cardiology 90: 410-417, 1995.
136.
Downey,
J.M., and Cohen, M.V.: Signal
Transduction in Ischemic Preconditioning.
Zeitschrift für Kardiologie 84 (Suppl 4): 77-86, 1995.
137.
Alpert,
M.A., Lambert, C.R., Terry, B.E., Cohen, M.V., Mukerji, V., Massey, C.V.,
Hashimi, M.W., and Panayiotou, H.:
Influence of Left Ventricular Mass on Left Ventricular Diastolic Filling
in Normotensive Morbidly Obese Subjects.
American Heart Journal 130: 1068-1073, 1995.
138.
Alpert,
M.A., Lambert, C.R., Panayiotou, H., Terry, B.E., Cohen, M.V., Massey, C.V.,
Hashimi, M.W., and Mukerji, V.:
Relation of Duration of Morbid Obesity to Left Ventricular Mass,
Systolic Function and Diastolic Filling and Effect of Weight Loss. American Journal of Cardiology 76:
1194-1197, 1995.
139.
Alpert,
M.A., Lambert, C.R., Terry, B.E., Cohen, M.V., Massey C.V., Hashimi, M.W.,
Panayiotou, H., and Mukerji, V.: Effect of Weight Loss on Left Ventricular
Diastolic Filling in Morbid Obesity.
American Journal of Cardiology 76: 1198-1201, 1995.
140.
Cohen,
M.V., and Downey, J.M.: Myocardial
Preconditioning Promises To Be a Novel Approach to the Treatment of Ischemic
Heart Disease. Annual Review of
Medicine 47: 21-29, 1996.
141.
Ardell,
J.L., Yang, X.-M., Barron, B.A., Downey, J.M., and Cohen, M.V.: Endogenous Myocardial Norepinephrine Is not
Essential for Ischemic Preconditioning in Rabbit Heart. American Journal of Physiology 270:
H1078-H1084, 1996.
142.
Goto,
M. Cohen, M.V., Van Wylen, D.G.L., and Downey J.M.: Attenuated Purine Production During Subsequent Ischemia in
Preconditioned Rabbit Myocardium Is Unrelated to the Mechanism of
Protection. Journal of Molecular and
Cellular Cardiology 28: 447-454, 1996.
143.
Downey,
J.M., and Cohen, M.V.: Preconditioning:
Markers vs. Epiphenomena. Basic
Research in Cardiology 91: 35-37, 1996.
144.
Wang,
P., Gallagher, K.P., Downey, J.M., and Cohen, M.V.: Pretreatment with Endothelin-1 Mimics Ischemic Preconditioning
Against Infarction in Isolated Rabbit Heart.
Journal of Molecular and Cellular Cardiology 28: 579-588, 1996.
145.
Yang,
X.-M., Baxter, G.F., Heads, R.J., Yellon, D.M., Downey, J.M., and Cohen,
M.V.: Infarct Limitation of the Second
Window of Protection in a Conscious Rabbit Model. Cardiovascular Research 31: 777-783, 1996.
146.
Cohen,
M.V., Liu, Y., Liu, G.S., Wang, P., Weinbrenner, C., Cordis, G.A., Das, D.K.,
and Downey, J.M.: Phospholipase D Plays
a Role in Ischemic Preconditioning in Rabbit Heart. Circulation 94: 1713-1718, 1996.
147.
Wang,
P., Downey, J.M., and Cohen, M.V.: Mast
Cell Degranulation Does Not Contribute to Ischemic Preconditioning in Isolated
Rabbit Hearts. Basic Research in
Cardiology 91: 458-467, 1996.
148.
Cope,
D.K., Impastato, W.K., Cohen, M.V., and Downey, J.M.: Volatile Anesthetics Protect the Ischemic Rabbit Myocardium from Infarction. Anesthesiology 86: 699-709, 1997.
149.
Yang,
X.-M., Sato, H., Downey, J.M., and Cohen, M.V.: Protection of Ischemic Preconditioning Is Dependent Upon a
Critical Timing Sequence of Protein Kinase C Activation. Journal of Molecular and Cellular Cardiology
29: 991-999, 1997.
150.
Cohen,
M.V., Thornton, J.D., Thornton, C.S., Sato, H., Miki, T., and Downey,
J.M.: Intravenous Co-infusion of
Adenosine and Norepinephrine Preconditions the Heart Without Adverse
Hemodynamic Effects. Journal of Thoracic
and Cardiovascular Surgery 114: 236-242, 1997.
151.
Weinbrenner,
C., Liu, G.-S., Cohen, M.V., and Downey, J.M.:
Phosphorylation of Tyrosine 182 of p38 Mitogen-activated Protein Kinase
Correlates with the Protection of Preconditioning in the Rabbit Heart. Journal of Molecular and Cellular Cardiology
29: 2383-2391, 1997.
152.
Downey,
J.M., and Cohen, M.V.: Signal
Transduction in Ischemic Preconditioning.
Advances in Experimental Medicine and Biology 430: 39-55, 1997.
153.
Maldonado,
C., Qiu Y., Tang, X.-L., Cohen, M.V., Auchampach, J., Bolli, R.: Role of Adenosine Receptors in Late
Preconditioning Against Myocardial Stunning in Conscious Rabbits. American Journal of Physiology 273:
H1324-H1332, 1997.
154.
Alpert,
M.A., Terry, B.E., Mulekar, M., Cohen, M.V., Massey, C.V., Fan, T.M.,
Panayiotou, H., and Mukerji, V.:
Cardiac Morphology and Left Ventricular Function in Normotensive
Morbidly Obese Patients With and Without Congestive Heart Failure, and Effect of
Weight Loss. American Journal of Cardiology
80: 736-740, 1997.
155.
Sato,
H., Miki, T., Vallabhapurapu, R.P., Wang, P., Liu, G.-S., Cohen, M.V., and
Downey, J.M.: The Mechanism of
Protection from 5-(N-ethyl-N-isopropyl)-amiloride Differs from that of Ischemic
Preconditioning in Rabbit Heart. Basic
Research in Cardiology 92: 339-350, 1997.
156.
Downey,
J.M., and Cohen, M.V.: Arguments in
Favor of Protein Kinase C Playing an Important Role in Ischemic
Preconditioning. Basic Research in
Cardiology 92 (Suppl 2): 37-39, 1997.
157.
Cohen,
M.V., Yang, X.-M., and Downey, J.M.:
Attenuation of S-T Segment Elevation During Repetitive Coronary
Occlusions Truly Reflects the Protection of Ischemic Preconditioning and Is Not
an Epiphenomenon. Basic Research in
Cardiology 92: 426-434, 1997.
158.
Downey,
J.M., and Cohen, M.V.: Preconditioning:
What It Is and How It Works. Dialogues
in Cardiovascular Medicine 2: 179-196, 1997.
159.
Baines,
C.P., Wang, L., Cohen, M.V., and Downey, J.M.:
Protein Tyrosine Kinase Is Downstream of Protein Kinase C for Ischemic
Preconditioning's Anti-Infarct Effect in the Rabbit Heart. Journal of Molecular and Cellular Cardiology
30: 383-392, 1998.
160.
Weinbrenner,
C., Liu, G.S., Downey, J.M., and Cohen, M.V.:
Cyclosporine A Limits Myocardial Infarct Size Even When Administered
After Onset of Ischemia. Cardiovascular
Research 38: 676-684, 1998.
161.
Weinbrenner,
C., Baines, C.P., Liu, G.-S., Armstrong, S.C., Ganote, C.E., Walsh, A.H.,
Honkanen, R.E., Cohen, M.V., and Downey, J.M.:
Fostriecin, an Inhibitor of Protein Phosphatase 2A, Limits Myocardial
Infarct Size Even When Administered After Onset of Ischemia. Circulation 98: 899-905, 1998.
162.
Cohen,
M.V., Downey, J.M., Gelpi, R.J., and Slezak, J.: Preface to Focussed Issue
“Myocardial Ischemia and Reperfusion”.
Molecular and Cellular Biochemistry 186: 1, 1998.
163.
Miki,
T., Cohen, M.V., and Downey, J.M.:
Opioid Receptor Contributes to Ischemic Preconditioning Through Protein
Kinase C Activation in Rabbits.
Molecular and Cellular Biochemistry 186: 3-12, 1998.
164.
Hashimi,
M.W., Thornton, J.D., Downey, J.M., and Cohen, M.V.: Loss of Myocardial Protection From Ischemic Preconditioning
Following Chronic Exposure to R(-)-N6-(2-Phenylisopropyl) Adenosine
Is Related to Defect at the Adenosine A1 Receptor. Molecular and Cellular Biochemistry 186:
19-25, 1998.
165.
Miki,
T., Liu, G.S., Cohen, M.V., and Downey, J.M.:
Mild Hypothermia Reduces Infarct Size in the Beating Rabbit Heart: A Practical Intervention for Acute
Myocardial Infarction? Basic Research
in Cardiology 93: 372-383, 1998.
166.
Iliodromitis,
E.K., Miki, T., Liu, G.S., Downey, J.M., Cohen, M.V., and Kremastinos,
D.T.: The PKC Activator PMA Preconditions
Rabbit Heart in the Presence of Adenosine Receptor Blockade: Is 5'-Nucleotidase
Important? Journal of Molecular and
Cellular Cardiology 30:2201-2211, 1998.
167.
Cohen,
M.V.: Preconditioning: An Experimental Phenomenon Awaiting the Chance for
Clinical Application. Alabama ACC Chapter Newsletter 7 (1):4-5, 1999.
168.
Cohen,
M.V., and Downey, J.M.: The Warm-up
Phenomenon and Ischemic Preconditioning: An Uncertain Relationship
(Editorial). European Heart Journal 20:167-168,
1999.
169.
Baines,
C.P., Liu, G.S., Birincioglu, M., Cohen, M.V., and Downey, J.M.: Ischemic Preconditioning Depends on
Interaction Between Mitochondrial KATP Channels and Actin
Cytoskeleton. American Journal of
Physiology 276:H1361-H1368, 1999.
170.
Miki,
T., Swafford, A.N., Cohen, M.V., and Downey, J.M.: Second Window of Protection Against Infarction in Conscious
Rabbits: Real or Artifactual. Journal of Molecular and Cellular Cardiology
31:809-816, 1999.
171.
Baines,
C.P., Cohen, M.V., and Downey, J.M.:
Signal Transduction in Ischemic Preconditioning: The Role of Kinases and
Mitochondrial KATP Channels.
Journal of Cardiovascular Electrophysiology 10:741-754, 1999.
172.
Miki,
T., Cohen, M.V., and Downey, J.M.:
Failure of N-2-Mercaptopropionyl Glycine to Reduce Myocardial Infarction
After 3 Days of Reperfusion in Rabbits.
Basic Research in Cardiology 94:180-187, 1999.
173.
Baines,
C.P., Wang, L., Cohen, M.V., and Downey, J.M.:
Myocardial Protection by Insulin Is Dependent on Phosphatidylinositol
3-Kinase but not Protein Kinase C or KATP Channels in the Isolated
Rabbit Heart. Basic Research in
Cardiology 94:188-198, 1999.
174.
Liu,
G.S., Cohen, M.V., Mochly-Rosen, D., and Downey, J.M.: Protein Kinase C-ε Is
Responsible for the Protection of Preconditioning in Rabbit Cardiomyocytes.
Journal of Molecular and Cellular Cardiology 31:1937-1948, 1999.
175.
Cohen,
M.V., Yang, X.-M., and Downey, J.M.: Smaller Infarct after Preconditioning Does
Not Predict Extent of Early Functional Improvement of Reperfused Heart. American Journal of Physiology 277:H1754-H1761,
1999.
176.
Birincioglu,
M., Yang, X.-M., Critz, S.D., Cohen, M.V., and Downey, J.M.: S-T Segment
Voltage During Sequential Coronary Occlusions Is an Unreliable Marker of
Preconditioning. American Journal of Physiology 277:H2435-H2441, 1999.
177.
Kim,
S.O., Baines, C.P., Critz, S.D., Pelech, S.L., Katz, S., Downey, J.M., and
Cohen, M.V.: Ischemia Induced Activation of Heat Shock Protein 27 Kinases and
Casein Kinase 2 in the Preconditioned Rabbit Heart. Biochemistry and Cell
Biology 77:559-567, 1999.
178.
Nakano,
A., Baines, C.P., Kim, S.O., Pelech, S.L., Downey, J.M., Cohen, M.V., and
Critz, S.D.: Ischemic Preconditioning Activates MAPKAPK2 in the Isolated Rabbit
Heart: Evidence for Involvement of p38 MAPK. Circulation Research 86:144-151,
2000.
179.
Cohen,
M.V., Baines, C.P., and Downey, J.M.: Ischemic Preconditioning: From Adenosine
Receptor to KATP Channel.
Annual Review of Physiology 62:79-109, 2000.
180.
Alpert,
M.A., Terry, B.E., Cohen, M.V., Fan, T.M., Painter, J.A., and Massey, C.V.: The
Electrocardiogram in Morbid Obesity. American Journal of Cardiology 85:908-910,
2000.
181.
Nakano,
A., Liu, G.S., Heusch, G., Downey, J.M., and Cohen, M.V.: Exogenous Nitric
Oxide Can Trigger a Preconditioned State Through a Free Radical Mechanism, But
Endogenous Nitric Oxide Is Not a Trigger of Classical Ischemic Preconditioning.
Journal of Molecular and Cellular Cardiology 32:1159-1167, 2000.
182.
Nakano,
A., Cohen, M.V., and Downey, J.M.: Ischemic Preconditioning: From Basic
Mechanisms to Clinical Applications.
Pharmacology & Therapeutics 86:263-275, 2000.
183.
Cohen,
M.V., Yang, X.-M., Neumann, T., Heusch, G. and Downey, J.M.: Favorable
Remodeling Enhances Recovery of Regional Myocardial Function in the Weeks
Following Infarction in Ischemically Preconditioned Hearts. Circulation 102:579-583,
2000.
184.
Downey,
J.M., and Cohen, M.V.: Do Mitochondrial KATP Channels Serve as
Triggers Rather Than End-effectors of Ischemic Preconditioning’s Protection?
Basic Research in Cardiology 95:272-274, 2000.
185.
Pain,
T., Yang, X.-M., Critz, S.D., Yankun, Y., Nakano, A., Liu, G.S., Heusch, G.,
Cohen, M.V., and Downey, J.M.: Opening of Mitochondrial KATP
Channels Triggers the Preconditioned State by Generating Free Radicals.
Circulation Research 87:460-466, 2000.
186.
Nakano,
A., Cohen, M.V., Critz, S., and Downey, J.M.: SB 203580, an Inhibitor of p38
MAPK, Abolishes Infarct-limiting Effect of Ischemic Preconditioning in Isolated
Rabbit Hearts. Basic Research in Cardiology 95:466-471, 2000.
187.
Heusch,
G., Liu, G.S., Rose, J., Cohen, M.V., and Downey, J.M.: No Confirmation for a
Causal Role of Volume-Regulated Chloride Channels in Ischemic Preconditioning
in Rabbits. Journal of Molecular and Cellular Cardiology 32:2279-2285,
2000.
188.
Xu,
Z., Yang, X.-M., Cohen, M.V., Neumann, T., Heusch, G., and Downey, J.M.:
Limitation of Infarct Size in Rabbit Hearts by the Novel Adenosine Receptor
Agonist AMP 579 Administered at Reperfusion. Journal of Molecular and Cellular
Cardiology 32:2339-2347, 2000.
189.
Baxter,
G.F., Hale, S.L., Miki, T., Kloner, R.A., Cohen, M.V., Downey, J.M., and
Yellon, D.M.: Adenosine A1 Agonist at Reperfusion Trial (AART):
Results of a Three-Center, Blinded, Randomized, Controlled Experimental Infarct
Study. Cardiovascular Drugs and Therapy
14:607-614, 2000.
190.
Krenz,
M., Baines, C.P., Heusch, G., Cohen, M.V., and Downey, J.M.: Acute Ethanol
Exposure Fails to Elicit Preconditioning-like Protection in in situ
Rabbit Hearts Because of Its Continued Presence During Ischemia. Journal of the
American College of Cardiology 37:601-607, 2001.
191.
Alpert,
M.A., Terry, B.E., Hamm, C.R., Fan, T.M., Cohen, M.V., Massey, C.V., and
Painter, J.A.: Effect of Weight Loss on the ECG of Normotensive Morbidly Obese
Patients. Chest 119:507-510, 2001.
192.
Downey,
J.M., and Cohen, M.V.: Mitochondrial KATP Channel Opening During
Index Ischemia and Following Myocardial Reperfusion in Ischemic Rat Hearts
(Editorial). Journal of Molecular and Cellular Cardiology 33:651-653,
2001.
193.
Cohen,
M.V., and Downey, J.M.: Can Pharmacologic Treatment Initiated Shortly Before
Reperfusion Salvage Ischemic Myocardium? Heart and Metabolism 12:9-13,
2001.
194.
Cohen,
M.V., Yang, X.-M., Liu, G.S., Heusch, G., and Downey, J.M.: Acetylcholine,
Bradykinin, Opioids, and Phenylephrine, but not Adenosine, Trigger
Preconditioning by Generating Free Radicals and Opening Mitochondrial KATP
Channels. Circulation Research 89:273-278, 2001.
195.
Yue,
Y., Krenz, M., Cohen, M.V., Downey, J.M., and Critz, S.D.: Menadione Mimics the
Infarct-Limiting Effect of Preconditioning in Isolated Rat Heart. American
Journal of Physiology 281:H590-H595, 2001.
196.
Xu,
Z., Downey, J.M., and Cohen, M.V.: AMP 579 Reduces Contracture and Limits
Infarction in Rabbit Heart by Activating Adenosine A2 Receptors.
Journal of Cardiovascular Pharmacology 38:474-481, 2001.
197.
Heusch,
G., Liu, G.S., Rose, J., Cohen, M.V., and Downey, J.M.: Swelling-Activated
Chloride Channels as Effectors of Ischemic Preconditioning? (Letter to the
Editor) Journal of Molecular and Cellular Cardiology 33:1891-1892, 2001.
198.
Schulz,
R., Cohen, M.V., Behrends, M., Downey, J.M., and Heusch, G.: Signal
Transduction of Ischemic Preconditioning.
Cardiovascular Research 52:181-198, 2001.
199.
Krenz,
M., Baines, C.P., Heusch, G., Downey, J.M., and Cohen, M.V.: Acute
Alcohol-Induced Protection Against Infarction in Rabbit Hearts: Differences
from and Similarities to Ischemic Preconditioning. Journal of Molecular and
Cellular Cardiology 33: 2015-2022, 2001.
200.
Xu,
Z., Cohen, M.V., Downey, J.M., Vanden Hoek, T.L., and Yao, Z.: Attenuation of
Oxidant Stress During Reoxygenation by AMP 579 in Cardiomyocytes. American
Journal of Physiology 281: H2585-H2589, 2001.
201.
Heusch,
G., Cohen, M..V., and Downey, J.M.: Ischemic Preconditioning Through Opening of
Swelling-Activated Chloride Channels? (Letter to the Editor) Circulation
Research 89: E48, 2001.
202.
Nakano,
A., Heusch, G., Cohen, M.V., and Downey, J.M.: Preconditioning One Myocardial
Region Does Not Necessarily Precondition the Whole Rabbit Heart. Basic Research
in Cardiology 97: 35-39, 2002.
203.
Gelpi,
R.J., Morales, C., Cohen, M.V., and Downey, J.M.: Xanthine Oxidase Contributes
to Preconditioning's Preservation of Left Ventricular Developed Pressure in
Isolated Rat Heart: Developed Pressure May Not Be an Appropriate End-Point for
Studies of Preconditioning. Basic Research in Cardiology 97: 40-46,
2002.
204.
Oldenburg,
O., Cohen, M.V., Yellon, D.M., and Downey, J.M.: Mitochondrial KATP
Channels: Role in Cardioprotection. Cardiovascular Research 55: 429-437,
2002.
205.
Oldenburg,
O., Qin, Q., Sharma, A.R., Cohen, M.V., Downey, J.M., and Benoit, J.N.:
Acetylcholine Leads to Free Radical Production Dependent on KATP
Channels, Gi Proteins, Phosphatidylinositol 3-Kinase and Tyrosine
Kinase. Cardiovascular Research 55: 544-552, 2002.
206.
Yue,
Y., Qin, Q., Cohen, M.V., Downey, J.M., and Critz, S.D.: The Relative Order of
mKATP Channels, Free Radicals and p38 MAPK in Preconditioning’s
Protective Pathway in Rat Heart. Cardiovascular Research 55: 681-689,
2002.
207.
Krenz,
M., Yang, X.-M., Qin, Q., Downey, J.M., and Cohen, M.V.: Dose-Response
Relationships of the Protective and Anti-Protective Effects of Acute Ethanol
Exposure in the Isolated Rabbit Heart. Heart Disease 4: 276-281, 2002.
208.
Krenz,
M., Oldenburg, O., Wimpee, H., Cohen, M.V., Garlid, K.D., Critz, S.D., Downey,
J.M., and Benoit, J.N.: Opening of ATP-Sensitive Potassium Channels Causes
Generation of Free Radicals in Vascular Smooth Muscle Cells. Basic Research in Cardiology
97: 365-373, 2002.
209.
Krieg,
T., Qin, Q., McIntosh, E.C., Cohen, M.V., and Downey, J.M.: ACh and Adenosine
Activate PI3-Kinase in Rabbit Hearts Through Transactivation of Receptor
Tyrosine Kinases. American Journal of Physiology 283: H2322-H2330, 2002.
210.
Oldenburg,
O., Kribben, A., Baumgart, D., Philipp, T., Erbel, R., and Cohen, M.V.:
Treatment of orthostatic hypotension. Current Opinion in Pharmacology 2:
740-747, 2002.
211.
Xu,
Z., Jiao, Z., Cohen, M.V., and Downey, J.M.: Protection from AMP 579 Can Be
Added to That from Either Cariporide or Ischemic Preconditioning in Ischemic
Rabbit Heart. Journal of Cardiovascular
Pharmacology 40: 510-518, 2002.
212.
Qin,
Q., Downey, J.M., and Cohen, M.V.: Acetylcholine But Not Adenosine Triggers
Preconditioning Through PI3-Kinase and a Tyrosine Kinase. American Journal of
Physiology 284: H727-H734, 2003.
213.
Krieg,
T., Landsberger, M., Alexeyev, M.F., Felix, S.B., Cohen, M.V., and Downey,
J.M.: Activation of Akt Is Essential for Acetylcholine to Trigger Generation of
Oxygen Free Radicals. Cardiovascular Research 58: 196-202, 2003.
214.
Oldenburg,
O., Cohen, M.V., and Downey, J.M.: Mitochondrial KATP Channels in
Preconditioning. Journal of Molecular and Cellular Cardiology 35:
569-575, 2003.
215.
Oldenburg,
O., Critz, S.D., Cohen, M.V., and Downey, J.M.: Acetylcholine-induced
Production of Reactive Oxygen Species in Adult Rabbit Ventricular Myocytes Is
Dependent on Phosphatidylinositol 3- and Src-Kinase Activation and
Mitochondrial KATP Channel Opening. Journal of Molecular and
Cellular Cardiology 35: 653-660, 2003.
216.
Krieg,
T., Cohen, M.V., and Downey, J.M.: Mitochondria and Their Role in
Preconditioning’s Trigger Phase. Basic Research in Cardiology 98:
228-234, 2003.
217.
Oldenburg,
O., Yang, X.-M., Krieg, T., Garlid, K., Cohen, M.V., Grover, G.J., and Downey,
J.M.: P1075 Opens Mitochondrial KATP Channels and Generates Reactive
Oxygen Species Resulting in Cardioprotection of Rabbit Hearts. Journal of
Molecular and Cellular Cardiology 35: 1035-1042, 2003.
218.
Xu,
Z., Downey, J.M., and Cohen, M.V.: Timing and Duration of Administration Are
Crucial for Antiinfarct Effect of AMP 579 Infused at Reperfusion in Rabbit
Heart. Heart Disease 5: 368-371, 2003.
219.
Oldenburg,
O., Qin, Q., Krieg, T., Yang, X.-M., Philipp, S., Critz, S.D., Cohen, M.V., and
Downey, J.M.: Bradykinin Induces Mitochondrial ROS Generation via NO, cGMP,
PKG, and mitoKATP Channel Opening and Leads to Cardioprotection.
American Journal of Physiology 286: H468-H476, 2003.
220.
Zhang,
S.J., Yang, X.-M., Liu, G.S., Cohen, M.V., Pemberton, K., and Downey, J.M.:
CGX-1051, a Peptide from Conus Snail Venom, Attenuates Infarction in Rabbit
Hearts when Administered at Reperfusion. Journal of Cardiovascular Pharmacology
42: 764-771, 2003.
221.
Cohen,
M.V.: Efficacy of Preconditioning Should Be Gauged by Reduction of Infarction
(Commentary: Minoxidil Opens KATP Channels and Confers
Cardioprotection. Authors: T. Sato, Y. Li, T. Saito, H. Nakaya). British
Journal of Pharmacology 141: 197-198, 2004.
222.
Yang,
X.-M., Krieg, T., Cui, L., Downey, J.M., and Cohen, M.V.: NECA and Bradykinin
at Reperfusion Reduce Infarction in Rabbit Hearts by Signaling Through PI3K,
ERK, and NO. Journal of Molecular and Cellular Cardiology 36:411-421,
2004.
223.
Krieg,
T., Cui, L., Qin, Q., Cohen, M.V., and Downey J.M.: Mitochondrial ROS
Generation Following Acetylcholine-Induced EGF Receptor Transactivation
Requires Metalloproteinase Cleavage of proHB-EGF. Journal of Molecular and
Cellular Cardiology 36: 435-443, 2004.
224.
Krenz,
M., Cohen, M.V., and Downey, J.M.: Protective and Anti-Protective Effects of
Acute Ethanol Exposure in Myocardial Ischemia/Reperfusion. Pathophysiology 10:
113-119, 2004.
225.
Krieg,
T., Yang, X.-M., Downey, J.M., Schaffer, S.W., and Cohen, M.V.: Augmented Taurine
Release Is Not the Mechanism of Ischemic Preconditioning’s Cardioprotection.
Amino Acids 26: 263-266, 2004.
226.
Cohen,
M.V.: Ions and Channels: New Answers to Old Questions. Journal of Molecular and Cellular Cardiology
37: 473-475, 2004.
227.
Qin,
Q., Yang, X.-M., Cui, L., Critz, S.D., Cohen, M.V., Browner, N.C., Lincoln,
T.M., and Downey, J.M.: Exogenous NO Triggers Preconditioning via a cGMP- and
mitoKATP-dependent Mechanism. American Journal of Physiology 287:
H712-H718, 2004.
228.
Yang,
X.-M., Proctor, J.B., Cui, Lin, Krieg, T., Downey, J.M., and Cohen, M.V.:
Multiple, Brief Coronary Occlusions During Early Reperfusion Protect Rabbit
Hearts by Targeting Cell Signaling Pathways. Journal of the American College of
Cardiology 44: 1103-1110, 2004.
229.
Krieg,
T., Qin, Q., Alexeyev, M.F., Cohen, M.V., and Downey, J.M.: Acetylcholine and
Bradykinin Trigger Preconditioning in the Heart Through a Pathway That Includes
Akt and NOS. American Journal of Physiology 287: H2606-H2611.
230.
Yang,
X.-M., Philipp, S., Downey, J.M., and Cohen, M.V.: Postconditioning’s
Protection Is Not Dependent on Circulating Blood Factors or Cells But Involves
Adenosine Receptors and Requires PI3-kinase and Guanylyl Cyclase Activation.
Basic Research in Cardiology 100: 57-63, 2005.
231.
Downey,
J.M. and Cohen, M.V.: We Think We See a Pattern Emerging Here. Circulation 111:
120-121, 2005.
232.
Krieg,
T., Cui, L., Dostmann, W.R.G., Downey, J.M., and Cohen, M.V.: Peptide Blockers
of PKG Inhibit ROS Generation by Acetylcholine and Bradykinin in Cardiomyocytes
But Fail to Block Protection in the Whole Heart. American Journal of Physiology
(in press).
233.
Critz,
S.D., Cohen, M.V., and Downey, J.M.: Mechanisms of Acetylcholine- and
Bradykinin-Induced Preconditioning. Vascular Pharmacology (in press).
Chapters
in Books
1. Cohen, M.V.: Experimental Physiology of Coronary Collaterals. In Current Cardiovascular
Topics: V.III. Eds. Donoso, E., and
Gorlin, R. Stratton Intercontinental
Medical Book Corp., New York, 1977, pp. 13-27.
2. Scheuer, J., and Cohen, M.V.: Approaches to Preserving Myocardial
Viability and Function in Acute Myocardial Infarction. I.
Basic Considerations. In
Current Cardiovascular Topics: V.IV.
Eds. Donoso, E., and Lipski, J.
Stratton Intercontinental Medical Book Corp., New York, 1978, pp. 37-59.
3. Cohen, M.V.: Limitations of Echocardiography.
In Current Cardiovascular Topics: V.VI. Ed. Donoso, E.
Stratton Intercontinental Medical Book Corp., New York, 1981, pp. 35-50.
4. Cohen, M.V.: Arterial and Venous Pulse Recordings, Apexcardiography,
Phonocardiography, and Systolic Time Intervals. In Goldberger, E.:
Textbook of Clinical Cardiology.
C.V. Mosby Co., St. Louis, 1982, pp. 83-122.
5. Rao, P.S., Cohen, M.V., and Mueller,
H.S.: Sequential Transcardiac Changes
in Free Radicals, Catecholamines and Lipid Peroxides in Early Experimental
Myocardial Ischemia. In Oxy
Radicals and Their Scavenger Systems.
V.II: Cellular and Medical
Aspects. Eds. Greenwald, R.A. and
Cohen, G. Elsevier Science Publishing
Co., Inc., New York, 1983, pp. 357-360.
6. Downey, J.M., and Cohen, M.V.: Nutrition of Ischemic Myocardium Through
Venous Level Collaterals. In Imaging Analysis and Simulation of the Cardiac
System. Eds. Sideman, S., and Beyar,
R. Freund Publishing House, London,
1990, pp. 335-362.
7. Cohen, M.V., and Downey, J.M.: Venous Level Collaterals in the Coronary
System. In Collateral
Circulation. Eds. Schaper, W., and Schaper, J.
Kluwer Academic Publishers, Dordrecht, The Netherlands, 1993, pp.
345-366.
8. Downey, J.M., Cohen, M.V., Ytrehus, K.,
and Liu, Y.: Cellular Mechanisms in
Ischemic Preconditioning: The Role of
Adenosine and Protein Kinase C. In
Cellular, Biochemical, and Molecular Aspects of Reperfusion Injury: Annals of the New York Academy of Sciences,
Vol. 723. Ed. Das, D.K. The New York Academy of Sciences, New York,
1994, pp. 82-98.
9. Downey, J.M, and Cohen, M.V.: Role of Adenosine in the Phenomenon of
Ischemic Preconditioning. In
Adenosine and Adenine Nucleotides: From
Molecular Biology to Integrative Physiology.
Eds. Belardinelli, L., and Pelleg, A.
Kluwer Academic Publishers, Boston, 1995, pp. 461-475.
10. Downey, J.M., Liu, G.S., and Cohen,
M.V.: Do Adenosine A3
Receptors Cause Preconditioning? In
Purines and Myocardial Protection. Eds. Abd-Elfattah, A.-S. A., and Wechsler,
A.S. Kluwer Academic Publishers,
Boston, 1996, pp. 447-458.
11. Downey, J.M., and Cohen, M.V.: Mechanisms of Preconditioning: Correlates and Epiphenomena. In Ischaemia: Preconditioning and Adaptation. Eds. Marber,
M.S., and Yellon, D.M. Bios Scientific
Publishers, Oxford, 1996, pp. 21-34.
12. Cohen, M.V., Liu, Y., and Downey,
J.M.: Activation of Protein Kinase C is
Critical to the Protection of Preconditioning.
In Myocardial Preconditioning. Eds. Parratt, J.R., and
Wainwright, C.L. R.G. Landes Co.,
Austin, TX, 1996, pp. 185-206.
13. Goto, M., Cohen, M.V., and Downey,
J.M.: The Role of Protein Kinase C in
Ischemic Preconditioning. In
Myocardial Preservation, Preconditioning, and Adaptation: Annals of the New York Academy of Sciences,
Vol. 793. Ed. Das, D.K. The New York Academy of Sciences, New York,
1996, pp. 177-190.
14. Liu, G.-S., Downey, J.M., and Cohen,
M.V.: Adenosine, Ischemia and
Preconditioning. In Purinergic
Approaches in Experimental Therapeutics. Eds. Jacobson, K.A., and Jarvis, M.F.
Wiley-Liss, Inc., New York, 1997, pp. 153-172.
15. Downey, J.M., and Cohen, M.V.: Signal Transduction in Ischemic Preconditioning. In Alfred Benzon Symposium 41: Coronary Microcirculation during Ischaemia
and Reperfusion. Eds. Haunsø, S., Aldershvile, J., and Svendsen, J.H.
Munksgaard, Copenhagen, 1997, pp. 339-355.
16. Downey, J.M., and Cohen, M.V.: Preconditioning. In Myocardial
Viability: A Clinical and Scientific Treatise. Ed. Dilsizian, V. Futura
Publishing Co., Inc., Armonk, New York, 2000, pp. 55-75.
1.
Cohen,
M.V., and Downey, J.M.: Ischemic Preconditioning: Description, Mechanism, and
Significance. In Heart Physiology and Pathophysiology, 4th
edition, Chapter 50. Eds. Sperelakis, N., Kurachi, Y., Terzic, A., and Cohen,
M.V. Academic Press, San Diego, 2000, pp. 867-885.
2.
Krenz,
M, Cohen, M.V., and Downey, J.M.: The Protective and Anti-Protective Effects of
Ethanol in a Myocardial Infarct Model. In Alcohol and Wine in Health and
Disease: Annals of the New York Academy
of Science, Vol 957. Ed. Das, D.K. and Ursini, F. The New York Academy of
Sciences, New York, 2002, pp. 103-114.
Books
1. Cohen, M.V.: Correlative Atlas of Adult Cardiac Disorders: Non-Invasive Diagnostic Techniques. Futura Publishing Company, Mount Kisco, New
York, 1980.
2. Cohen, M.V.: Coronary Collaterals:
Clinical and Experimental Observations.
Futura Publishing Company, Mount Kisco, New York, 1985.
Editorship
1. Cohen, M.V., Downey, J.M., Gelpi, R.J.,
and Slezák, J.: Guest editors for
focused issue on “Myocardial Ischemia and Reperfusion”. Mol Cell Biochem 186:1-203, 1998.
2. Sperelakis, N., Kurachi, Y., Terzic,
A., and Cohen, M.V.: Editors for Heart Physiology and Pathophysiology, 4th
edition. Academic Press, San Diego,
2000.
1.
Tsuchida,
A., Ardell, J.L., Cohen, M.V., Downey, J.M., Hamrick, M.L., Heymann, A., and
Jones, C.E.: Effect of Chronic
Ventricular Sympathectomy on Coronary Collateral Flow and Infarction in Dogs.
2.
Oldenburg,
O., Yang, X.-M., Krieg, T., Zhang, S.-J., Downey, J.M., and Cohen, M.V.:
Ischemic Preconditioning, But Not AT1-Receptor Blockade, Attenuates
Collagen Deposition and Improves Regional Myocardial Function in Rabbits After
Myocardial Infarction.
3.
Philipp,
S., Yang, X.-M., Cui, L., Downey, J.M., and Cohen, M.V.: Postconditioning Must
Be Initiated in Less Than 1 Minute Following Reperfusion and Is Dependent on
Adenosine A2b Receptors
and PI3-kinase.
4.
Yang,
X.-M., Philipp, S., Downey, J.M., and Cohen, M.V.: Atrial Natriuretic Peptide
at Reperfusion Limits Infarction in Rabbit Hearts by Activation of PKG and
Opening of mKATP Channels.
5.
Solenkova,
N.V., Cohen, M.V., and Downey, J.M.: Ischemic preconditioning activates
adenosine receptors, PI3-kinase and ERK 1/2 During Reperfusion.
6.
Philipp,
S., Cui, L., Cohen, M.V., and Downey, J.M.: Prolyl Hydroxylase Inhibitors
Protect Myocardium by Mitochondrial ROS Generation.
7.
Costa,
A.D.T., Garlid, K.D., West, I.C., Downey, J.M., Cohen, M.V., and Critz, S.D.:
Protein Kinase G Transmits the Cardioprotective Signal from Cytosol to
Mitochondria.
8.
Xu,
Z., Mueller, R.A., Park, S.-S., Boysen, P.G., Cohen, M.V., and Downey, J.M.:
Cardioprotection with Adenosine A2 Receptor Activation at
Reperfusion.
Abstracts
1.
Cohen,
M.V., Cohn, P.F., Herman, M.V., and Gorlin, R.: Diagnosis and Prognosis of Main Left Coronary Artery
Obstruction. Presented American
Heart Association, October, 1971.
Circulation 44: II-102, 1971.
2.
Chahine,
R., Cohen, M.V., Klein, M.D., and Gorlin, R.:
The Effect of Acetylstrophanthidin on Systolic Time Intervals in
Man. Clinical Research 20: 366,
1972.
3.
Cohen,
M.V., Downey, J.M., Eldh, P., Urschel, C.W., Sonnenblick, E.H., and Kirk,
E.S.: The Effects of Nitroglycerin on
Coronary Collaterals and Myocardial Contractility. Presented American Federation for Clinical Research,
Eastern Section, January, 1973. Clinical Research 20: 854, 1972.
4.
Cohen,
M.V., Downey, J.M., Eldh, P., Urschel, C.W., Sonnenblick, E.H., and Kirk,
E.S.: Enhancement of Myocardial
Contractility by Dilatation of Coronary Collaterals. Presented American College of Cardiology, February,
1973. American Journal of Cardiology 31:
126, 1973.
5.
Cohen,
M.V., and Kirk, E.S.: Autoregulation
and Tachyphylaxis in Small and Large Coronary Arteries. Presented American Society of
Pharmacology and Experimental Therapeutics, April, 1973. Federation Proceedings 32: 793, 1973.
6.
Bergeron,
G., Cohen, M.V., Teichholz, L.E., and Gorlin, R.: Echocardiographic Analysis of Mitral Valve Motion after
Myocardial Infarction. Clinical
Research 21: 404, 1973.
7.
Kirk,
E.S., Cohen, M.V., and Sonnenblick, E.H.:
Role of Shunting in Negative Inotropy of Intracoronary Angiotensin. Clinical Research 21: 429, 1973.
8.
Cohen,
M.V., Downey, J.M., Sonnenblick, E.H., and Kirk, E.S.: Preservation of Myocardial Function by
Antegrade and Retrograde Flow in Collaterals.
Journal of Clinical Investigation 52: 19a, 1973.
9.
Kirk,
E.S., Cohen, M.V., and Sonnenblick, E.H.:
Role of Shunting in Negative Inotropy of Intracoronary Angiotensin. Circulation 48: IV-186, 1973.
10.
Teichholz,
L.E., Cohen, M.V., Sonnenblick, E.H., and Gorlin, R.: Detection of Abnormalities of Left Ventricular Wall Motion by
B-Scan Ultrasonography. Presented American Heart Association, November,
1973. Circulation 48: IV-127,
1973.
11.
Bergeron,
G., Cohen, M.V., Teichholz, L.E., and Gorlin, R.: The Effects of Acute Myocardial Infarction on Mitral Valve
Diastolic Velocity. Presented
American Heart Association, November, 1973.
Circulation 48: IV-48, 1973.
12.
Cohen,
M.V., Sonnenblick, E.H., and Kirk, E.S.:
Coronary Steal: Role in
Detrimental Effect of Isoproterenol Following Acute Coronary Occlusion. Presented American College of
Cardiology, February, 1974. American
Journal of Cardiology 33: 131, 1974.
13.
Levine,
J.A., Cohen, M.V., and Kirk, E. S.:
Norepinephrine Infusion Following Coronary Occlusion: Ischemic Injury Limited by Enhanced
Collateral Flow. Presented
American College of Cardiology, February, 1974. American Journal of Cardiology 33: 151, 1974.
14.
Cohen,
M.V., and Kirk, E.S.: Reduction of
Epicardial ST-Segment Elevation Following Increased Myocardial Ischemia: Experimental and Theoretical
Demonstration. Presented
American Federation for Clinical Research, National Meeting, May, 1974. Clinical Research 22: 269A, 1974.
15.
Cohen,
M.V., Holman, B.L., Levine, J., Downey, J.M., Eldh, P., Sonnenblick, E.H., and
Kirk, E.S.: Preservation of Jeopardized
Myocardium by Collateral Blood Flow.
Journal of Clinical Investigation 53: 16a, 1974.
16.
Cooperman,
L.B., Rosenblum, R., and Cohen, M.V.:
Abnormal Septal Contraction in Idiopathic Hypertrophic Subaortic
Stenosis. Presented American
Heart Association, November, 1974.
Circulation 50: III-29, 1974.
17.
Cohen,
M.V., Holman, B.L., and Kirk, E.S.:
Coronary Collaterals:
Determinant of Infarct Size. Presented
American Federation for Clinical Research, Eastern Section, January, 1975. Clinical Research 22: 678A, 1974.
18.
Cohen,
M.V., Holman, B.L., and Kirk, E.S.:
Coronary Collaterals: Determinant
of Infarct Size. Clinical Research 23:
176A, 1975.
19.
Bensman,
M., Delman, A. and Cohen, M.V.:
Phonocardiographic Follow-up of Patients with Late Systolic Murmur
and/or Midsystolic Click. Circulation 52:
II-159, 1975.
20.
Cohen,
M.V., and Yipintsoi, T.: Measurement of
True Collateral Flow to Ischemic Myocardium.
Presented American Federation for Clinical Research, Eastern
Section, January, 1976. Clinical
Research 23: 562A, 1975.
21.
Cohen,
M.V., Yipintsoi, T., Malhotra, A., and Scheuer, J.: Effect of Exercise on Coronary Collateral Function. Presented American College of
Cardiology, February, 1977. American
Journal of Cardiology 39: 262, 1977.
22.
Greenberg,
M.A., Cohen, M.V., and Herman, L.S.:
Premature Mitral Valve Closure in Atrial Flutter. Presented American Federation for
Clinical Research, Eastern Section, October, 1978. Clinical Research 26: 600A, 1978.
23.
Cohen,
M.V., and Yipintsoi, T.: Coronary
Collateral Flow: Determinant of
Myocardial Ischemia and Cardiac Function.
Clinical Research 27: 159A, 1979.
24.
Cohen,
M.V., and Yipintsoi, T.: Coronary Steal
in Conscious Dogs: Fact or Fancy. Presented American Federation for
Clinical Research, National Meeting, May, 1980. Clinical Research 28: 161A, 1980.
25.
Cohen,
M.V., and Yipintsoi, T.: Coronary
Collaterals: Role in Restoration of
Blood Flow and Preservation of Cardiac Function During Exercise. Clinical Research 28: 161A, 1980.
26.
Cohen,
M.V., and Yipintsoi, T.: Coronary
Collaterals: Role in Restoration of
Blood Flow and Preservation of Cardiac Function During Exercise. Presented XXVIII International
Congress of Physiological Sciences:
Symposium on Coronary Circulation, Bad Nauheim, F.R.G., July, 1980. Proceedings of XXVIII International Congress
of Physiological Sciences, p. 38.
27.
Cohen,
M.V., Yipintsoi, T., and Scheuer, J.: Exercise
Training Stimulates Coronary Collateral Development. Presented American Heart Association, November, 1980. Circulation 62: III-65, 1980.
28.
Cohen,
M.V.: Coronary Steal Caused by
Renografin. Clinical Research 26:
182A, 1981.
29.
Grose,
R., Greenberg, M.A., Steingart, R., Bontemps, R., and Cohen, M.V.: Left Ventricular Volumes During Relief of
Cardiac Tamponade in Man. Clinical
Research 29: 200A, 1981.
30.
Cohen,
M.V.: Coronary Reserve and Resistance
in Physiologic Cardiac Hypertrophy. Presented
American Federation for Clinical Research, National Meeting, May, 1982. Clinical Research 30: 179A, 1982.
31.
Cohen,
M.V., Steingart, R., Bontemps, R., Rabinowitz, A., and Wexler, J.: Shrinking Exercise-Tl Perfusion Defect
Following Coronary Occlusion. Presented
American Federation for Clinical Research, National Meeting, May, 1982. Clinical Research 30: 179A, 1982.
32.
Rao,
P.S., Cohen, M.V., and Mueller, H.S.:
Sequential Transcardiac Changes in Thromboxane B2 and Free
Radicals in Early Experimental Myocardial Ischemia. Presented American Federation for Clinical Research,
National Meeting, April, 1983. Clinical
Research 31: 213A, 1983.
33.
Steingart,
R.M., and Cohen, M.V.: Quantitation of
Exercise Coronary Flow Limitation with Thallium Scintigraphy. Presented American Federation for
Clinical Research, National Meeting, April, 1983. Clinical Research 31: 220A, 1983.
34.
Rao,
P.S., Cohen, M.V., and Mueller, H.S.:
Transcardiac Production of Thromboxane, Prostacyclin and Free Radicals
in Early Experimental Myocardial Ischemia.
Presented American Heart Association, November, 1983. Circulation 68: III-185, 1983.
35.
Grose,
R.M., Strain, J.E., and Cohen, M.V.:
Premature Pulmonic Valve Closure in Acute Experimental Mitral
Regurgitation. Presented
American Heart Association, November, 1983.
Circulation 68: III-305, 1983.
36.
Greenberg,
M.A., Grose, R.M., Strain, J.E., McGinnis, J., and Cohen, M.V.: Decreased Coronary Dilatory Response in
Syndrome X. Presented American
Heart Association, November, 1984.
Circulation 70: II-21, 1984.
37.
Cohen,
M.V., Steingart, R., and Rao, P.S.:
Lack of Effect of Prior Exercise Training on Infarct Size and
Exercise-Induced Ischemia after Coronary Occlusion. Presented American Heart Association, November, 1984. Circulation 70: II-178, 1984.
38.
Matsuki,
T., Shirato, C., Cohen, M.V., and Downey, J.M.: Oxipurinol and Allopurinol Reduce Infarct Size in Reperfused Dog
Heart Without Pretreatment. Presented
American Physiological Society, August, 1987.
Physiologist 30: 187, 1987.
39.
Cohen,
M.V., and Downey, J.M.: Coronary Venous
Flow During Angioplasty Is Not Equivalent to Collateral Flow. Presented American Heart Association,
November, 1987. Circulation 76:
IV-184, 1987.
40.
Nejima,
J., Canfield, D.R., Manders, W.T., Knight, D.R., Cohen, M.V., Fallon, J.T., and
Vatner, S.F.: Failure of Superoxide
Dismutase and Catalase to Alter Size of Infarct and Functional Recovery in
Conscious Dogs with Reperfusion. Presented
American Heart Association, November, 1987.
Circulation 76: IV-198, 1987.
41.
Cohen,
M.V., Matsuki, T., and Downey, J.M.:
Coronary Venous Retroperfusion--Effects on Myocardial Nutritive Blood
Flow. Presented American College
of Cardiology, February, 1988. Journal
of the American College of Cardiology 11: 65A, 1988.
42.
Matsuki,
T., Cohen, M.V., Holt, G., Hearse, D.J., and Downey, J.M.: Chronic Sympathetic Denervation Fails to
Augment Coronary Collateral Flow or Limit Infarct Size in Rabbit. Presented American Physiological Society, May, 1988. FASEB Journal 2: A946, 1988.
43.
Gutowski,
T., Adelson, R., and Cohen, M.V.:
Physician Non-Recognition of Lipid Abnormalities in Patients Referred
for Cardiac Catheterization. Clinical
Research 36: 281A, 1988.
44.
Roth,
J.A., and Cohen, M.V.: Voxel-Based
Three-Dimensional (3D) Cardiac Echo Reconstruction: In-Vitro Validation. Presented
American Federation for Clinical Research, National Meeting, May, 1988. Clinical Research 36: 312A, 1988.
45.
Downey,
J.M., Matsuki, T., Cohen, M.V., Ayling, J.E., and Hearse, D.J.: Chronic Chemical Sympathectomy Does Not
Protect the Ischemic Rabbit Heart. Presented
International Society for Heart Research (European Section), September,
1988. Journal of Molecular and Cellular
Cardiology 20 (Suppl V): S69, 1988.
46.
Gutowski,
T., Adelson, R., and Cohen, M.V.: Poor
Acceptance of Blood Lipids as Treatable Risk Factor Among Cardiologists. Presented American Heart Association,
November, 1988. Circulation 78:
II-384, 1988.
47.
Downey,
J.M., Matsuki, T., Cohen, M.V., Ayling, J.E., and Hearse, D.J.: Chronic Chemical Sympathectomy Fails to
Protect the Rabbit Heart from Ischemia. Presented American Heart
Association, November, 1988.
Circulation 78: II-643, 1988.
48.
Uemura,
N., Shen, Y.-T., Cohen, M.V., Nejima, J., Thomas, J.X., Knight, D.R., and
Vatner, S.F.: Collateral Blood Flow and
Infarct Development in Beagles vs. Mongrel Dogs. Presented American
Physiological Society, March, 1989.
FASEB Journal 3: A1306, 1989.
49.
Roth,
J.A., and Cohen, M.V.: Voxel-Based
Three-Dimensional (3D) Cardiac Echo Imaging:
Accuracy and Reproducibility. Presented
American Heart Association, November, 1989.
Circulation 80: II-569, 1989.
50.
50. Cohen, M.V., Vernon, J., Buttrick, P.,
and Hatcher, V.B.: Enhanced Fibroblast
Growth Factor Activity in Ischemic and Infarcting Dog Myocardium. Clinical Research 38: 489A, 1990.
51.
Marantz,
P.R., Kuwabara, Y., Tobin, J.N., Derby, C., Comer, C., and Cohen, M.V.: Diastolic Left Ventricular Dysfunction in
the Elderly: Pathological Phenomenon or
Normal Aging? Presented Society
of General Internal Medicine, May, 1990.
Clinical Research 38: 699A, 1990.
52.
Cohen,
M.V., Liu, G.S., and Downey, J.M.:
Preconditioning by a Brief Coronary Occlusion Preserves Wall Motion in
Ischemia/Reperfusion. Presented
American Heart Association, November, 1990.
Circulation 82: III-271, 1990.
53.
53. Cohen, M.V.: Coronary Collateral Development:
Is Absence of Coronary Reserve a Necessary Prerequisite? Presented American Heart Association, November, 1991. Circulation 84: II-96 1991.
54.
Charney,
R., Schwinger, M.E., Cohen, M.V., Menegus, M., Spindola-Franco, H., and
Greenberg, M.A.: Dobutamine
Echocardiography Predicts Recovery of Hibernating Myocardium Following Coronary
Revascularization. Presented
American College of Cardiology, April, 1992.
Journal of the American College of Cardiology 19: 176A,
1992.
55.
Cohen,
M.V.: Beta-Blockade Fails to Inhibit
Coronary Collateral Development. Presented
American Federation for Clinical Research, National Meeting, May, 1992. Clinical Research 40: 276A, 1992.
56.
Cohen,
M.V.: Brief Coronary Occlusions Prior
to More Prolonged One Salvage Ischemic Myocardium, Reduce Infarct Size and
Promote Recovery of Systolic Function. Presented
Satellite Symposium of XIV World Congress of the International Society for
Heart Research, Sapporo, Japan, May, 1992.
Journal of Molecular and Cellular Cardiology 24 (Suppl II): S5,
1992.
57.
Walsh,
R.S., Borges, M., Thornton, J., and Cohen M.V.: Hypoxia Preceding Ischemia Reduces Infarction Despite the Lack of
an Intervening Period of Reoxygenation.
Presented American Heart Association, November, 1992. Circulation 86: I-342, 1992.
58.
Thornton,
J., Liu, Y., Cohen, M.V., Downey, J., and Schaffer, S.W.: Metabolic Effects of Diabetes Mellitus
Protect Ischemic Myocardium from Infarction.
Presented American Heart Association, November, 1992. Circulation 86: I-828, 1992.
59.
Walsh,
R.S., Richards, S.C., Liu, G.S., Cohen, M.V., and Downey, J.M.: Role of Adenosine Receptor Subtypes in
Preconditioning. Presented
American College of Cardiology, March , 1993.
Journal of the American College of Cardiology 21: 116A, 1993.
60.
Liu,
G.S., Yang, X., Tsuchida, A., Arnoult, S., Thornton, J., Cope, D., Cohen, M.V.,
and Downey, J.M.: Ischemic
Preconditioning Can Be Reinstated in Rabbit Hearts. Presented Federation of American Societies for
Experimental Biology, March, 1993.
FASEB Journal 7: A119, 1993.
61.
Yang,
X., Snell, K., Downey, J.M., and Cohen, M.V.:
Brief Repetitive Myocardial Ischemia Does Not Stimulate Collateral
Growth in Rabbits. Presented Federation of American Societies for
Experimental Biology, March, 1993.
FASEB Journal 7: A320, 1993.
62.
Thornton,
J.D., Daly, J.F., Cohen, M.V., and Downey, J.M.: Catecholamines Can Protect Ischemic Myocardium But Are Not
Involved in Ischemic Preconditioning. Presented
Federation of American Societies for Experimental Biology, March, 1993. FASEB Journal 7: A418, 1993.
63.
Tsuchida,
A., Ardell, J., Cohen, M.V., Downey, J., Heymann, A., Barron, B.A., Hamrick,
M., and Jones, C.: Elimination of
Myocardial Catecholamines with Ventricular Sympathectomy Fails to Limit Infarct
Size in Canine Heart. Presented
American Heart Association, November, 1993.
Circulation 88: I-42, 1993.
64.
Ytrehus,
K., Cohen, M.V., and Downey, J.: Volume
of Risk Zone Influences Infarct Size in Rabbits and May Account for Unexplained
Variability in Infarction Studies. Presented
American Heart Association, November, 1993.
Circulation 88: I-137, 1993.
65.
Cohen,
M.V., Yang, X.-M., and Downey, J.M.:
Multiple Brief Episodes of Myocardial Ischemia Abolish Protection of
Ischemic Preconditioning Seen After 1 Episode of Brief Ischemia. Presented American Heart Association,
November, 1993. Circulation 88:
I-138, 1993.
66.
Walsh,
R.S., Daly, J.J., Cohen, M.V., and Downey J.M.: Blockade of Both Adenosine and Alpha-Adrenergic Receptors Is
Required to Prevent Hypoxic Preconditioning in Rabbit Hearts. Presented American College of
Cardiology, March, 1994. Journal of the
American College of Cardiology 23: 396A, 1994.
67.
Tsuchida,
A., Liu, Y., Liu, G., Cohen, M.V., and Downey, J.M.: α1-Adrenergic Agonists Can Precondition
Myocardium Through Direct Activation of Protein Kinase C. Presented American College of
Cardiology, March, 1994. Journal of the
American College of Cardiology 23: 396A, 1994.
68.
Snell,
K.S., Tsuchida, A., Van Wylen, D.G.L., Downey, J.M., and Cohen, M.V.: ATP-Sensitive Potassium Channels Fail to
Regulate Cardiac Interstitial Fluid Adenosine Levels. Presented Federation of American Societies for
Experimental Biology, April, 1994.
FASEB Journal 8: A560, 1994.
69.
Cohen,
M.V.: Protein Kinase C Plays a Central
Role in the Protection of Ischemic and Pharmacological Preconditioning. Presented International Society for
Heart Research, July, 1994. Journal of
Molecular and Cellular Cardiology. 26:
CXLIV, 1994.
70.
Yang,
X.-M., Cohen, M.V., Burckhartt, B., Tsuchida, A., Mullane, K., and Downey,
J.M.: Acadesine Extends Window of
Protection for Preconditioning. Presented
International Society for Heart Research, July, 1994. Journal of Molecular and Cellular Cardiology. 26: CL, 1994.
71.
Hashimi,
W., Downey, J.M., and Cohen, M.V.: Loss
of Preconditioning's Protection After Chronic Adenosine Exposure Is Not Related
to PKC Downregulation. Presented
International Society for Heart Research, July, 1994. Journal of Molecular and Cellular Cardiology. 26: CLII, 1994.
72.
Liu,
Y., Tsuchida, A., Cohen, M.V., and Downey, J.M.: Pretreatment with Angiotensin II Limits Infarction in Rabbit
Hearts. Presented International
Society for Heart Research, July, 1994.
Journal of Molecular and Cellular Cardiology. 26: CLV, 1994.
73.
Hashimi,
W., Thornton, J.D., Downey, J.M., and Cohen, M.V.: Chronic Adenosine A1-Agonist Exposure Results in
Adenosine Receptor Rather Than G protein Downregulation. Presented American Heart Association,
November, 1994. Circulation 90:
I-107, 1994.
74.
Ardell
J.L., Yang, X.-M., Thornton, J.D., Swafford, A., Cohen, M.V., and Downey,
J.M.: Depletion of Norepinephrine by
Chronic Surgical Sympathectomy Does Not Block Protection from Ischemic
Preconditioning. Presented American
Heart Association, November, 1994.
Circulation 90: I-108, 1994.
75.
Liu,
Y., Cohen, M.V., and Downey, J.M.:
Chelerythrine, a Highly Selective Protein Kinase C Inhibitor, Blocks
Anti-Infarct Effect of Ischemic Preconditioning in Rabbit Hearts. Presented American Heart Association,
November, 1994. Circulation 90:
I-207, 1994.
76.
Goto,
M., Liu, Y., Ardell, J.L., Cohen, M.V., and Downey, J.M.: Bradykinin Limits Myocardial Infarction in
Rabbits by Protein Kinase C Activation and Not by Nitric Oxide Synthesis. Presented American Heart Association,
November, 1994. Circulation 90:
I-208, 1994.
77.
Downey,
J.M., and Cohen, M.V.: Signal
Transduction in Ischemic Preconditioning:
A Putative Role for Protein Kinase C.
Presented German Cardiac
Society, April, 1995.
78.
Ardell,
J.L., Yang, X.-M., Cohen, M.V., and Downey, J.M.: Depletion of Norepinephrine by Reserpine Increases the Threshold
for Protection by Ischemic Preconditioning.
Presented Federation of American Societies for Experimental
Biology, April, 1995. FASEB Journal 9:
A879, 1995.
79.
Goto,
M., Tsuchida, A., Liu, Y., Cohen, M.V., and Downey, J.M.: Transient Inhibition of Glucose Uptake Can
Protect Rabbit Heart. Presented
International Society for Heart Research, May, 1995. Journal of Molecular and Cellular Cardiology 27: A27,
1995.
80.
Yang,
X.-M., Baxter, G.F., Yellon, D.M., Fletcher, J.R., Downey, J.M., and Cohen,
M.V.: Second Window of Protection in
Conscious Rabbits. Presented
International Society for Heart Research, May, 1995. Journal of Molecular and Cellular Cardiology 27: A27,
1995.
81.
Liu,
Y., Cordis, G.A., Das, D.K., Downey, J.M., and Cohen, M.V.: Protein Kinase C May Be Activated by
Phospholipase D Rather Than C in Ischemic Preconditioning. Presented International Society for
Heart Research, May, 1995. Journal of
Molecular and Cellular Cardiology 27: A41, 1995.
82.
Ardell,
J.L., Liu, Y., Yang, X.-M., Cohen, M.V., and Downey, J.M.: Triggering of Ischemic Preconditioning
Involves Bradykinin in In Situ but Not In Vitro Rabbit
Hearts. Presented International
Society for Heart Research, May, 1995.
Journal of Molecular and Cellular Cardiology 27: A44, 1995.
83.
Liu,
G.S., Cohen, M.V., and Downey, J.M.:
Phospholipase D Is Involved in Preconditioning of Rabbit Myocytes. Presented International Society for
Heart Research, May, 1995. Journal of
Molecular and Cellular Cardiology 27: A44, 1995.
84.
Wang,
P., Gallagher, K., Downey, J.M., and Cohen, M.V.: Endothelin-1 Limits Myocardial Infarction Through PKC Activation. Presented International Society for
Heart Research, May, 1995. Journal of
Molecular and Cellular Cardiology 27: A44, 1995.
85.
Cope,
D.K., Impastato, K., Cohen, M.V., and Downey, J.M.: Adenosine Receptors Are Necessary for Protection of Ischemic
Rabbit Myocardium by Halothane. Presented
International Society for Heart Research, May, 1995. Journal of Molecular and Cellular Cardiology 27: A47,
1995.
86.
Baxter,
G.F., Yang, X.-M., Heads, R.J., Yellon, D.M., Fletcher, J.R., Downey, J.M. and
Cohen, M.V.: Myocardial Protection 24 H
after Preconditioning in Conscious Rabbits.
Presented Satellite
Symposium of XV World Congress of the International Society for Heart Research,
Venice, Italy, June 1995. Journal of
Molecular and Cellular Cardiology 27: A397, 1995.
87.
Cohen,
M.V., Yang, X.-M., Fletcher, J.R., and Downey, J.M.: Less ST Segment Elevation During Subsequent Coronary Occlusions
Indicates Preconditioning in Rabbit. Presented
International Society for Heart Research, July, 1995. Journal of Molecular and Cellular Cardiology 27: A144,
1995.
88.
Yang,
X.-M., Fletcher, J.R., Downey, J.M., and Cohen, M.V.: The Long Ischemia Is the Critical Time for Kinase Activity During
Ischemic Preconditioning. Presented
International Society for Heart Research, July, 1995. Journal of Molecular and Cellular Cardiology 27: A157,
1995.
89.
Liu,
G.S., Cohen, M.V., and Downey, J.M.:
Preconditioning of Rabbit Myocytes Depends on Activation of
Phospholipase D. Presented
American Heart Association, November, 1995.
Circulation 92: I-135, 1995.
90.
Hashimi,
W., Yang, X.-M., Lambert, C., Downey, J.M., and Cohen, M.V.: Bradykinin May Be the Drug of Choice for
Preconditioning the Heart in the Clinical Setting. Presented American Heart Association, November, 1995. Circulation 92: I-456, 1995.
91.
Alpert,
M.A., Lambert, C.R., Terry, B.E., Massey, C.V., and Cohen, M.V.: Effect of Weight Loss on Left Ventricular Diastolic
Filling in Morbidly Obese Subjects. Presented
American Heart Association, November, 1995.
Circulation 92: I-472, 1995.
92.
Liu,
G.S., Cohen, M.V., and Downey, J.M.:
Rabbit Ventricular Myocytes Can Be Preconditioned by Activation of
Protein Kinase C-Coupled Receptors. Presented
American College of Cardiology, March, 1996.
Journal of the American College of Cardiology 27: 33A, 1996.
93.
Goto,
M., Cohen, M.V., and Downey, J.M.:
Attenuated Purine Release from Preconditioned Rabbit Myocardium is
Unrelated to Protection. Presented
American College of Cardiology, March, 1996.
Journal of the American College of Cardiology 27: 194A, 1996.
94.
Liu,
G., Critz, S., Chujo, M., Cohen, M.V., Downey, J.M.: Pinacidil but not nicorandil opens KATP Channels in
Rabbit Myocytes and Mimics Ischemic Preconditioning. Presented International Society for Heart Research, June,
1996. Journal of Molecular and Cellular
Cardiology 28: A164, 1996.
95.
Prasad
V., R., Wang, P., Cohen, M.V., and Downey, J.M.: Inhibition of Na+-H+ Exchange Late in
Ischemia Reduces Infarct Size. Presented
International Society for Heart Research, June, 1996. Journal of Molecular and Cellular Cardiology 28: A167,
1996.
96.
Yang,
X.-M., Cohen, M.V., and Downey, J.M.:
The Sustained Ischemia Is the Critical Time for Kinase Activity During
Ischemic Preconditioning. Presented
International Society for Heart Research, June, 1996. Journal of Molecular and Cellular Cardiology 28: A186,
1996.
97.
Yang,
X.-M., Downey, J.M., and Cohen, M.V.: Diminution
of ST Segment Deviation in Sequential Coronary Occlusions Is a True Indicator
of Preconditioning. Presented
International Society for Heart Research, June, 1996. Journal of Molecular and Cellular Cardiology 28: A188,
1996.
98.
Miki,
T., Sato, H., Cohen, M.V., and Downey, J.M.:
Opioid Receptor Contributes to Ischemic Preconditioning Through Protein
Kinase C Activation in Rabbits. Presented
American Heart Association, November, 1996.
Circulation 94: I-392-I-393, 1996.
99.
Weinbrenner,
C., Wang, P., Cohen, M.V., and Downey, J.M.:
Glycogen Loss During Preconditioning Does Not Correlate with
Protection. Presented American
Heart Association, November, 1996.
Circulation 94: I-424, 1996.
100.
Baines,
C.P., Cohen, M.V., and Downey, J.M.:
Protein Tyrosine Kinase Inhibitor, Genistein, Blocks Preconditioning in
Isolated Rabbit Hearts. Presented
American Heart Association, November, 1996.
Circulation 94: I-661, 1996.
101.
Cope,
D.K., Impastato, W.K., Cohen, M.V., and Downey, J.M.: Halothane Administered Before or During
Ischemia Reduces Infarction. Presented
International Society for Heart Research, July, 1997. Journal of Molecular and Cellular Cardiology 29: A170,
1997.
102.
Liu,
G.S., Cohen, M.V., and Downey, J.M.:
Protection of Cardiomyocytes by Mild Cooling Plus Preconditioning Is
Additive. Presented
International Society for Heart Research, July, 1997. Journal of Molecular and Cellular Cardiology 29: A198,
1997.
103.
Liu,
G.S., Honkanen, R., Cohen, M.V., and Downey, J.M.: Inhibition of Protein Phosphatase 2A Protects Rabbit
Cardiomyocytes. Presented
International Society for Heart Research, July, 1997. Journal of Molecular and Cellular Cardiology 29: A198,
1997.
104.
Weinbrenner,
C., Cohen, M.V., and Downey, J.M.: Phosphorylation
of P38 MAP Kinase Correlates With the Protection of Ischemic
Preconditioning. Presented
International Society for Heart Research, July, 1997. Journal of Molecular and Cellular Cardiology 29: A203,
1997.
105.
Baines,
C.P., Honkanen, R.E., Cohen, M.V., and Downey, J.M.: Fostriecin Limits Infarction Even When Infused After the Onset of
Ischemia. Presented
International Society for Heart Research, July, 1997. Journal of Molecular and Cellular Cardiology 29: A204,
1997.
106.
Miki,
T., Cohen, M.V., and Downey, J.M.: Mild
Hypothermia Reduces Infarct Size in the Beating Rabbit Heart. Presented International Society for
Heart Research, July, 1997. Journal of
Molecular and Cellular Cardiology 29: A210, 1997.
107.
Liu,
G.S., Baines, C.P., Cohen, M.V., and Downey, J.M.: Activation of P38 Mitogen-Activated Protein Kinase Is Involved in
Ischemic Preconditioning in Rabbit Heart.
Presented American Heart Association, November, 1997. Circulation 96: I-71, 1997.
108.
Weinbrenner,
C., Downey, J.M., and Cohen, M.V.:
Cyclosporine A Preconditions Rabbit Heart When Administered Before as
Well as After Onset of Ischemia. Presented
American Heart Association, November, 1997.
Circulation 96: I-252, 1997.
109.
Baines,
C.P., Wang, L., Downey, J.M., and Cohen, M.V.:
Cardioprotection by Insulin is Dependent on Phosphatidylinositol
3-Kinase but Not Protein Kinase C. Presented
American Heart Association, November, 1997.
Circulation 96: I-573-I-574, 1997.
110.
Weinbrenner,
C., Baines, C.P., Honkanen, R.E., Cohen, M.V., and Downey, J.M.: Ischemic Preconditioning in the Rabbit Heart
Does Not Protect by Inhibiting Protein Phosphatase 1 or 2A. Presented American Heart Association,
November, 1997. Circulation 96:
I-574, 1997.
111.
Miki,
T., Cohen, M.V., and Downey, J.M.:
Hypothermia's Cardioprotective Effect Is Additive to That of Ischemic
Preconditioning. Presented
American Heart Association, November, 1997.
Circulation 96: I-687, 1997.
112.
Weinbrenner,
C., Downey, J.M., Cohen, M.V.:
Cyclosporin A präkonditioniert das Kaninchenherz auch nach dem Beginn
der Myokardischämie. Presented
Deutschen Gesellschaft für Herz- und Kreislaufforschung, April, 1998. Zeitshrift für Kardiologie 87: I-76,
1998.
113.
Weinbrenner,
C., Baines C.P., Honkanen, R.E., Cohen, M.V., Downey, J.M.: Die ischämische Präkonditionierung im
Kaninchenherzen ist nicht durch die Inhibition der Proteinphosphatasen 1 oder
2A vermittelt. Presented
Deutschen Gesellschaft für Herz- und Kreislaufforschung, April, 1998. Zeitshrift für Kardiologie 87: I-194,
1998.
114.
Miki,
T., Swafford, A.N., Cohen, M.V., and Downey, J.M.: Second Window of Protection in Conscious Rabbits: Real or Artifactual. Presented International Society for
Heart Research, May, 1998. Journal of
Molecular and Cellular Cardiology 30: A74, 1998.
115.
Liu,
G.S., Cohen, M.V., and Downey, J.M.:
Involvement of Cytoskeletal Actin in Preconditioned Rabbit
Myocytes. Presented
International Society for Heart Research, August, 1998. Journal of Molecular and Cellular Cardiology
30: A262, 1998.
116.
Trammell,
B.W., Pain, S., Downey, J.M., Cohen, M.V., and Critz, S.D.: MAPKAPK2 Is Activated in Preconditioned
Rabbit Heart. Presented
International Society for Heart Research, August, 1998. Journal of Molecular and Cellular Cardiology
30: A265, 1998.
117.
Baines,
C.P., Cohen, M.V., and Downey, J.M.:
Myocardial Protection by Anisomycin Is Mediated by ATP-Sensitive K+
Channels. Presented
International Society for Heart Research, August, 1998. Journal of Molecular and Cellular Cardiology
30: A265, 1998.
118.
Liu,
G.S., Mochly-Rosen, D., Cohen, M.V., and Downey, J.M.: Protein Kinase C-ε, Not δ, Is
Responsible for the Protection of Preconditioning in Rabbit
Cardiomyocytes. Presented
American Heart Association, November, 1998.
Circulation 98: I-71, 1998.
119.
Baines,
C.P., Liu, G.S., Birincioglu, M., Cohen, M.V., and Downey, J.M.: Diazoxide, a Mitochondrial KATP-Channel
Opener, Is Cardioprotective in Ischemic Rabbit Myocardium. Presented American Heart Association,
November, 1998. Circulation 98:
I-343, 1998.
120.
Cohen,
M.V., Yang, X.-M., and Downey, J.M.:
Ischemic Preconditioning Improves Post-Ischemic Myocardial Function in
Conscious Rabbits. Presented
American Heart Association, November, 1998.
Circulation 98: I-485, 1998.
121.
Liu,
G.S., Cohen, M.V., and Downey, J.M.:
Hypo-osmotic Stress Protects Rabbit Cardiomyocytes. Presented American Heart Association,
November, 1998. Circulation 98:
I-585, 1998.
122.
Liu,
G.S., Baines, C., Birincioglu, M., Cohen, M.V., and Downey, J.M.: KATP Channel Is Involved in the
Protection From an Activator of P38 MAP Kinase in Rabbit Hearts. Presented American Heart Association,
November, 1998. Circulation 98:
I-585, 1998.
123.
Kim,
S.O., Pain, T.S., Pelech, S.L., Cohen, M.V., Katz, S., and Downey, J.M.:
Activation of MAPKAP Kinase 2 During Ischemia in Preconditioned Rabbit Heart. Presented
American Heart Association, November, 1998.
Circulation 98: I-585, 1998.
124.
Krenz,
M., Baines, C.P., Yang, X.-M., Cohen, M.V., and Downey, J.M.: Acute Ethanol
Exposure Does Not Limit Infarct Size in In Situ Rabbit Hearts. Presented
International Society for Heart Research, June, 1999. Journal of Molecular and
Cellular Cardiology 31: A10, 1999.
125.
Liu,
G.S., Cohen, M.V., Mochly-Rosen, D., and Downey, J.M.: Protection from
Non-Selective PKC Activation Can Be Aborted by Blockade of Only
PKC-ε. Presented
International Society for Heart Research, June, 1999. Journal of Molecular and
Cellular Cardiology 31: A17, 1999.
126.
Baines,
C.P., Cohen, M.V., and Downey, J.M.: Acute Ethanol Exposure Limits Infarct Size
in Isolated Rabbit Hearts by a Preconditioning-Like Mechanism. Presented
International Society for Heart Research, June, 1999. Journal of Molecular and
Cellular Cardiology 31: A17, 1999.
127.
Fan,
T.-H.M., Xu, J., Pain, T., Cohen, M.V., and Downey, J.M.: Ischemic
Preconditioning Inhibits Mitochondrial Cytochrome C Release in Ischemic Rabbit
Myocardium. Presented
International Society for Heart Research, June, 1999. Journal of Molecular and
Cellular Cardiology 31: A33, 1999.
128.
Pain,
T., Cohen, M.V., and Downey, J.M.: Mitochondrial KATP Channels May
Play a Role in Preconditioning’s Memory. Presented International Society
for Heart Research, June, 1999. Journal of Molecular and Cellular Cardiology 31:
A33, 1999.
129.
Nakano,
A., Kim, S.O., Pelech, S.L., Downey, J.M., Cohen, M.V., and Critz, S.D.:
Activation of MAPKAPK2 Is Involved in Preconditioned Rabbit Heart. Presented International Society for
Heart Research, June, 1999. Journal of Molecular and Cellular Cardiology 31:
A43, 1999.
130.
Liu,
G.S., Cohen, M.V., and Downey, J.M.: Inhibition of Nitric Oxide Synthesis Does
Not Affect Ischemic Preconditioning in Isolated, Perfused Rabbit Hearts. Presented American Heart Association,
November 1999. Circulation 100: I-243, 1999.
131.
Nakano,
A., Baines, C.P., Kim, S.O., Pelech, S.L., Pain, T.S., Downey, J.M., Cohen,
M.V., and Critz, S.D.: MAPKAPK2, but Not JNK, Is Activated During Ischemia in
Preconditioned Hearts. Presented
American Heart Association, November 1999. Circulation 100: I-325, 1999.
132.
Pain,
T.S., Cohen, M.V., and Downey, J.M.: The Mitochondrial KATP Channel
May Be a Trigger Rather Than the End-effector of Preconditioning’s Anti-infarct
Effect. Presented American Heart
Association, November 1999. Circulation 100: I-342, 1999.
133.
Yang,
X.-M., Downey, J.M., and Cohen, M.V.: HMR 1883, a Surface KATP
Channel Antagonist, Blocks Protection From Diazoxide: Diazoxide’s Specificity
for Mitochondrial KATP Is Questionable. Presented American Heart Association, November 1999.
Circulation 100: I-342, 1999.
134.
Fan,
T.-H.M., Xu, J., Pain, T.S., Krenz, M., Cohen, M.V., and Downey, J.M.:
Diazoxide Inhibits Mitochondrial Cytochrome C Release in Ischemic Rabbit
Myocardium. Presented American
Heart Association, November 1999. Circulation 100: I-630, 1999.
135.
Krenz,
M., Heusch, G., Cohen, M.V., and Downey, J.M.: Inhibition of JAK-2 Does Not
Block Ischemic Preconditioning in Rats.
Presented International Society for Heart Research, June, 2000.
Journal of Molecular and Cellular Cardiology 32: A19, 2000.
136.
Nakano,
A., Liu, G.S., Heusch, G., Downey, J.M., and Cohen, M.V.: Exogenous, But Not
Endogenous, Nitric Oxide Triggers Preconditioning of the Isolated Rabbit Heart
by Formation of Free Radicals. Presented
International Society for Heart Research, June, 2000. Journal of Molecular and
Cellular Cardiology 32: A24, 2000.
137.
Krenz,
M., Xu, Z., Baines, C.P., Heusch, G., Cohen, M.V. and Downey, J.M.: Acute
Ethanol Exposure Is Protective Both In Vitro and In Situ, But
Only if Washed Out Before Ischemia. Presented
International Society for Heart Research, June, 2000. Journal of Molecular and
Cellular Cardiology 32: A45, 2000.
138.
Yang,
X.-M., Pain, T., Heusch, G., Cohen, M.V., and Downey, J.M.: Diazoxide Protects
the Heart by Release of Free Radicals. Presented
International Society for Heart Research, June, 2000. Journal of Molecular and
Cellular Cardiology 32: A49, 2000.
139.
Xu,
Z., Cohen, M.V., Heusch, G., and Downey, J.M.: AMP 579 Started During Ischemia
Limits Infarct Size in Rabbit Hearts. Presented
International Society for Heart Research, June, 2000. Journal of Molecular and
Cellular Cardiology 32: A55, 2000.
140.
Cohen,
M.V., Yang, X.-M., Neumann, T., Heusch, G., and Downey, J.M.: Ischemic
Preconditioning Causes Favorable Myocardial Remodeling Resulting in Long-term
Improvement of Regional Cardiac Function. Presented American Heart
Association, November 2000. Circulation 102: II-121, 2000.
141.
Xu,
Z., Cohen, M.V., Heusch, G., and Downey, J.M.: Amp579 at Reperfusion Limits
Infarct Size in Crystalloid-Perfused Rabbit Hearts. Presented American
Heart Association, November 2000. Circulation 102: II-272, 2000.
142.
Yang,
X.-M., Heusch, G., Downey, J.M., and Cohen, M.V.: Acetylcholine, But Not
Adenosine, Triggers Cardiac Preconditioning by Causing Release of Free Radicals
and Opening of Mitochondrial KATP Channels. Presented
American Heart Association, November 2000. Circulation 102: II-287,
2000.
143.
Krenz,
M., Wimpee, H., Cohen, M.V., Downey, J.M., and Benoit, J.N.: Opening of
Mitochondrial ATP-Sensitive Potassium Channels Generates Reactive Oxygen
Species in Vascular Smooth Muscle Cells. Presented Experimental Biology,
March 2001. FASEB J 15: A488, 2001.
144.
Oldenburg,
O., Krenz, M., Cohen, M.V., Downey, J.M., and Benoit, J.N.: Mitochondrial K+
Influx Per Se Causes Generation of Reactive Oxygen Species in Vascular
Smooth Muscle Cells. Presented International Society for Heart Research,
July, 2001. Journal of Molecular and Cellular Cardiology 33: A87, 2001.
145.
Xu,
Z., Cohen, M.V., and Downey, J.M.: Protective Effect of AMP 579 Depends on
Drug's Timing of Administration and Can Be Added to That of Ischemic
Preconditioning. Presented
International Society for Heart Research, July, 2001. Journal of Molecular and
Cellular Cardiology 33: A132, 2001.
146.
Yang,
X.-M., Krenz, M., Downey, J.M., and Cohen, M.V.: Protective and Anti-Protective
Effects of Acute Ethanol Exposure Have Similar Thresholds in Isolated Rabbit
Hearts. Presented International Society for Heart Research, July, 2001.
Journal of Molecular and Cellular Cardiology 33: A133, 2001.
147.
Critz,
S.D., Yue, Y., Cohen, M.V., and Downey, J.M.: Menadione Preconditions Rat Heart
by Stimulating Production of Cardiac Mitochondrial Free Radicals Which Activate
PKC and P38 MAPK. Presented
American Heart Association, November, 2001. Circulation 104: II-101,
2001.
148.
Zhelong,
X., Downey, J.M., and Cohen, M.V.: Adenosine Does Not Duplicate the
Anti-Infarct Effect of AMP 579 at Reperfusion Although the Two Agents Have the
Same Receptors. Presented American Heart Association, November, 2001.
Circulation 104: II-149, 2001.
149.
Zhelong,
X., Cohen, M.V., Downey, J.M., Vanden Hoek, T.L., and Yao, Z.: Differential
Effects of AMP 579 and Adenosine on Free Radical Burst at Reoxygenation in
Isolated Chick Cardiomyocytes Subjected to Simulated Ischemia. Presented American Heart Association,
November, 2001. Circulation 104: II-149, 2001.
150.
Oldenburg,
O., Cohen, M.V., Downey, J. M., and Benoit, J.N.: Acetylcholine Leads to Free
Radical Production Dependent on KATP Channels, Gi
Proteins, Phosphatidylinositol 3-, and Tyrosine Kinases. Presented
Experimental Biology, April 2002. FASEB Journal 16: A452, 2002.
151.
Qin,
Q., Cohen, M.V., and Downey, J.M.: Acetylcholine But Not Adenosine Triggers
Preconditioning Through PI3-Kinase and a Tyrosine Kinase. Presented
Experimental Biology, April 2002. FASEB Journal 16: A855, 2002.
152.
Krieg,
T., Qin, Q., Critz, S.D., Cohen, M.V., and Downey, J.M.: Acetylcholine
Activates Akt in Myocardium Confirming a Role for Phosphatidylinositol 3-Kinase
in Acetylcholine’s Cardioprotection. Presented Experimental Biology,
April 2002. FASEB Journal 16: A856, 2002.
153.
Oldenburg,
O., Mochly-Rosen, D., Cohen, M.V., and Downey, J.M.: Acetylcholine-Induced
Production of Reactive Oxygen Species in A7r5 Cells is Dependent on Protein
Kinase C. Presented International Society for Heart Research, July,
2002. Journal of Molecular and Cellular Cardiology 34: A30, 2002.
154.
Qin,
Q., Oldenburg, O., Cohen, M.V., and Downey J.M.: The Potassium Ionophore
Valinomycin Mimics Preconditioning and Generates Reactive Oxygen Species. Presented
International Society for Heart Research, July, 2002. Journal of Molecular and
Cellular Cardiology 34: A33, 2002.
155.
Krieg,
T., Qin, Q., Cohen, M.V., and Downey, J.M.: Acetylcholine Activates
Phosphatidylinositol 3-Kinase via Transactivation of the EGF Receptor. Presented
International Society for Heart Research, July, 2002. Journal of Molecular and
Cellular Cardiology 34: A36, 2002.
156.
Yang,
X.-M., Krieg, T., Downey, J.M., and Cohen, M.V.: NECA Limits Infarction in
Rabbit Heart by Activating Adenosine A2 Receptor and PI3-Kinase. Presented
International Society for Heart Research, July, 2002. Journal of Molecular and
Cellular Cardiology 34: A36, 2002.
157.
Krieg,
T., Qin, Q., Cohen, M.V., and Downey, J.M.: Acetylcholine and Adenosine
Activate Phosphatidylinositol 3-Kinase Through Transactivation of Receptor
Tyrosine Kinases in a Src-Dependent Manner. Presented American Heart
Association, November, 2002. Circulation 106: II-7, 2002.
158.
Oldenburg,
O., Cohen, M.V., Downey, J.M.: Acetylcholine-induced Production of Reactive
Oxygen Species in Adult Rabbit Myocytes Is Dependent on Phosphatidylinositol
3-Kinase Activation and Mitochondrial KATP Channel Opening. Presented
American Heart Association, November, 2002. Circulation 106: II-230,
2002.
159.
Qin,
Q., Cohen, M.V., and Downey, J.M.: Acetylcholine But Not Adenosine Triggers
Preconditioning by a Pathway Involving Src and PI3 Kinases. Presented
American Heart Association, November, 2002. Circulation 106: II-314,
2002.
160.
Oldenburg,
O., Cohen, M.V., and Downey, J.M.: Acetylcholine-Induced Production of Reactive
Oxygen Species in Ventricular Myocytes Is Dependent on Phosphatidylinositol 3-
and Src-Kinase Activation, and Mitochondrial KATP Channel Opening. Presented
Deutschen Gesellschaft für Herz- und Kreislaufforschung, April, 2003. Zeitshrift für Kardiologie 92 (Suppl
I): 132, 2003.
161.
Oldenburg,
O., Cohen, M.V., and Downey, J.M.: Bradykinin Leads to Generation of Reactive
Oxygen Species in Cardiomyocytes by Activation of B2-Receptor and Opening of
Mitochondrial KATP Channels via PKG. Presented International Society for
Heart Research, June 2003. European Journal of Heart Failure Supplements 2:
44, 2003.
162.
Krieg,
T., Yang, X.-M., Downey, J., and Cohen, M.V.: Bradykinin and NECA But Not
Acetylcholine at Reperfusion Limit Infarction in Rabbit Heart Through
Activation of PI3-kinase. Presented International Society for Heart
Research, June 2003.
163.
European
Journal of Heart Failure Supplements 2: 46, 2003.
164.
Cohen,
M.V.: Protecting the Ischemic Heart at Reperfusion. Presented
International Society for Heart Research, June 2003. Journal of Molecular and
Cellular Cardiology 35: A-19, 2003.
165.
Pemberton,
K., Zhang, S.-J., Cohen, M.V., and Downey, J.M.: The Conopeptide CGX-1051 Administered
at Reperfusion Limits Infarct Size with No Hemodyanmic Effects. Presented International Society for
Heart Research, June 2003. Journal of Molecular and Cellular Cardiology 35:
A-28, 2003.
166.
Qin,
Q., Yang, X.-M., Cohen, M.V., Critz, S.D., and Downey, J.M.: Bradykinin
Protects Rabbit Hearts by a NO- and CGMP-Dependent Pathway. Presented International
Society for Heart Research, June 2003. Journal of Molecular and Cellular
Cardiology 35: A-29, 2003.
167.
Krieg,
T., Cohen, M.V., and Downey, J.M.: Mitochondrial ROS Generation Following
Acetylcholine in Cardiomyocytes Invovles EGF Receptor Transactivation and
Metalloproteinase Cleavage of proHB-EGF. Presented International Society
for Heart Research, June 2003. Journal of Molecular and Cellular Cardiology 35:
A-46, 2003.
168.
Qian,
X., Cohen, M.V., Downey, J.M., and Critz, S.D.: Cyclic GMP Triggers p38 MAPK
Activation in H9c2 Cells and Rabbit Cardiomyocytes. Presented
International Society for Heart Research, June 2003. Journal of Molecular and
Cellular Cardiology 35: A-49, 2003.
169.
Yang,
X.-M., Oldenburg, O., Downey, J.M., and Cohen, M.V.: Ischemic Preconditioning,
But Not AT1 Blockade, Attenuates Collagen Deposition and Improves
Regional Myocardial Function Following Ischemia in Rabbit Hearts. Presented
International Society for Heart Research, June 2003. Journal of Molecular and
Cellular Cardiology 35: A-49, 2003.
170.
Bailey,
S.W., Malinow, M.R., Hess, D.L., Upson, B.M., Graf, E., Cohen, M.V., Nozawa,
M., Alverson, P.B., and Ayling, J.E.: Folic Acid Pharmacokinetics:
Dose-Dependent Metabolism. Presented 4th International
Homocysteine Conference, June 2003. Journal of Inherited Metabolic Disease 26
(Suppl 1): 122, 2003.
171.
Krieg,
T., Cui, L., Cohen, M.V., and Downey, J.M.: Acetylcholine-induced EGF Receptor
Transactivation Requires Metalloproteinase Cleavage of pro-HB-EGF to Generate
Mitochondrial ROS. Presented American Heart Association, November 2003.
Circulation 108: IV-93, 2003.
172.
Yang,
X.-M., Downey, J.M., and Cohen, M.V.: Multiple, Brief Coronary Occlusions
During Early Reperfusion Protect Rabbit Hearts by Activation of ERK and
Production of Nitric Oxide. Presented American Heart Association,
November 2003. Circulation 108: IV-158, 2003.
173.
Bailey,
S.W., Malinow, M.R., Hess, D.L., Upson, B.M., Graf, E., Cohen, M.V., Nozawa,
M., Alverson, P.B., and Ayling, J.E.: Dose Dependent Lack of Metabolism of
Folic Acid in Humans. Presented Experimental Biology, April 2004. FASEB
Journal 18: A176, 2004.
174.
Yang,
X.-M., Cui, L., Krieg, T., Downey, J.M., and Cohen, M.V.: Postconditioning
Protects Isolated Hearts Through PI3K Signaling. Presented International
Society for Heart Research, May 2004. Journal of Molecular and Cellular
Cardiology 36: 613, 2004.
175.
Krieg,
T., Qin, Q., Alexeyev, M.F., Cohen, M.V., and Downey, J.M.: Acetylcholine
Preconditions by Activating Akt and NOS to generate ROS. Presented
International Society for Heart Research, June 2004. Journal of Molecular and Cellular
Cardiology 36: 741, 2004.
176.
Garlid,
K.D., Costa, A.D., Cohen, M.V., Downey, J.M., and Critz, S.D.: Cyclic GMP and
PKG Activate mito KATP Channels in Isolated Mitochondria. Presented
Satellite Conference of International Society for Heart Research, August 2004.
Cardiovascular Journal of South Africa 15
(Suppl 1): S5, 2004.
177.
Yang,
X.-M., Downey, J.M., and Cohen, M.V.: Postconditioning’s Protection Is Not
Dependent on Circulating Blood Factors or Cells but Requires PI3-kinase and
Guanylyl Cyclase Activation. Presented American Heart Association,
November 2004. Circulation 110: III-168, 2004.
178.
Philipp,
S., Downey, J.M., and Cohen, M.V.: Postconditioning Must Be Initiated in Less
Than 1 Minute Following Reperfusion and Is Dependent on Adenosine Receptors and
PI3-Kinase. Presented American Heart Association, November 2004.
Circulation 110: III-168, 2004.
179.
Cohen,
M.V. and Downey, J.M.: Signaling in Postconditioning: A New Cardioprotective
Intervention with Clinical Potential. Presented International Society
for Heart Research, June 2005. Journal of Molecular and Cellular Cardiology 38:
000, 2005.
180.
Philipp,
S., Cui, L., Solodushko, V., Cohen, M.V., and Downey, J.M.: Activation of Erk Is
Essential for Opening MitoKATP Channels by
Gi
Protein-Coupled Receptors. Presented International Society for Heart
Research, June 2005. Journal of Molecular and Cellular Cardiology 38:
000, 2005.
181.
Yang,
X.-M., Downey, J.M., and Cohen, M.V.: Atrial Natriuretic Peptide (ANP) at
Reperfusion Limits Infarction in Rabbit Hearts by Activation of PKG and Opening
of mKATP Channels. Presented International Society for Heart
Research, June 2005. Journal of Molecular and Cellular Cardiology 38:
000, 2005.
182.
Philipp,
S., Cui, L., Cohen, M.V., and Downey, J.M.: Prolyl Hydroxylase Inhibitors
Protect the Heart by Inducing Mitochondrial ROS Generation via NO, cGMP, PKG,
and mitoKATP. Presented International Society for Heart
Research, June 2005. Journal of Molecular and Cellular Cardiology 38:
000, 2005.
183.
Solenkova,
N., Cohen, M.V., and Downey, J.M.: Ischemic Preconditioning Protects the Heart
Through Adenosine Receptor Activation During Reperfusion. Presented
International Society for Heart Research, June 2005. Journal of Molecular and
Cellular Cardiology 38: 000, 2005.
184.
Solenkova,
N., Cohen, M.V., and Downey, J.M.: PI3 Kinase Supports the Preconditioned Heart
Through a Critical Convalescent Period. Presented International Society
for Heart Research, June 2005. Journal of Molecular and Cellular Cardiology 38:
000, 2005.
Revised 03/24/05